DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4598 and hadhaa

DIOPT Version :9

Sequence 1:	NP_001260304.1	Gene:	CG4598 / 34315	FlyBaseID:	FBgn0032160	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001098746.1	Gene:	hadhaa / 553401	ZFINID:	ZDB-GENE-031222-5	Length:	761	Species:	Danio rerio

Alignment Length:	280	Identity:	68/280 - (24%)
Similarity:	109/280 - (38%)	Gaps:	71/280 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    17 RMMSTATKL---TTVEVNDKTGIATLTMNRP--PVNGLNLELLQDLKSSIDEIESNKS-RGLILT 75
            |.:|.::.:   |.|....|..:|.:.:|.|  .||.|:..:..::...::|:..|.| :..:|.
Zfish    25 RSLSVSSAVLARTHVSYEVKDNVAVVRINDPTSKVNTLSKHMQAEMVEVMNEVWGNSSVKSAVLI 89

  Fly    76 SSSSTIFSAGLDILEMYKPDKDRIRAFWTQLQDTWLALYG---------SSVPTAAAINGHSPAG 131
            |.....|.||.||        :.|:|..|..:.|.|:..|         |.:|..|||||....|
Zfish    90 SRKPGCFIAGADI--------NMIQACTTAEEVTSLSQAGQKMFEQIEKSPIPIVAAINGSCLGG 146

  Fly   132 GCLLATSCEYRVMVPN--FTIGLNETQLGIVAPQWFMASFLSVLPQRIAERA----LNQGRMFTT 190
            |...|.:|:||:...:  ..:|..|..||::..    |.....||:.:...|    :..||....
Zfish   147 GLEFAIACQYRIATKSKKTVLGTPEVMLGLLPG----AGGTQRLPKMVGLPAAFDMMLTGRNIRA 207

  Fly   191 EEALKVGLIDETANNKEEAIEKCVAFIGTFAKVNPLARSLTKQQFR--------AADLQQLQNGR 247
            ::|.|:||:.:.                    |:||...|...:.|        |.|..:....:
Zfish   208 DKAKKMGLVHQL--------------------VDPLGPGLKSPEERTIEYLEEVAVDFAKGLAAK 252

  Fly   248 KEDLEKFLFFVNQPAVQKGL 267
            |..|||          :|||
Zfish   253 KVTLEK----------KKGL 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	51/207 (25%)
hadhaa	NP_001098746.1	fa_ox_alpha_mit	25..760	CDD:131494	68/280 (24%)
		crotonase-like	39..249	CDD:119339	58/241 (24%)
		3HCDH_N	361..539	CDD:280833
		3HCDH	542..637	CDD:279114
		3HCDH	674..>750	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.810