DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4598 and eci2

DIOPT Version :9

Sequence 1:	NP_001260304.1	Gene:	CG4598 / 34315	FlyBaseID:	FBgn0032160	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001002645.3	Gene:	eci2 / 436918	ZFINID:	ZDB-GENE-040718-392	Length:	392	Species:	Danio rerio

Alignment Length:	246	Identity:	49/246 - (19%)
Similarity:	103/246 - (41%)	Gaps:	35/246 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    27 TVEVNDKTGIATLTMNRP-PVNGLNLELLQDLKSSIDEIESNKSRGLILTSSSSTIFSAGLD--- 87
            |:.|:.:..|.|:.:||| ..|.:.:|:..:|..:: |:.......:.:.:.:...:.:|.|
Zfish   139 TLLVSTEDNITTIRLNRPDKKNAITVEMYNELIEAL-ELAGKDDSVITVMTGNGDYYCSGNDLNN 202

  Fly    88 --------ILEMYKPDKDRIRAFWTQLQDTWLALYGSSVPTAAAINGHSPAGGCLLATSCEYRVM 144
                    :.:|.|...:.:|.:..       |......|....|||  ||.|..:.....:.|:
Zfish   203 FTKIPEGGVEKMAKDAGELLRRYVK-------AYIDFPKPLIGVING--PAVGVSVTLLGLFDVV 258

  Fly   145 --VPNFTIGLNETQLGIVAPQWFMASFLSVLPQRI----AERALNQGRMFTTEEALKVGLIDETA 203
              ....|.....:||| .:|:. .:|:|  .|:.:    |...|...:..:..:|.::||:.|..
Zfish   259 YATEKATFHTPFSQLG-QSPEG-CSSYL--FPKMMGAAKASEVLLFNKKLSATQACELGLVSEVF 319

  Fly   204 NNKEEAIEKCV-AFIGTFAKVNPLARSLTKQQFRAADLQQLQNGRKEDLEK 253
              .|.:.:..| :.:..:||:...:.:|:||..|..:.::|......::|:
Zfish   320 --PESSFQSEVWSRLKAYAKLPKNSLALSKQLIRGLEKEKLHAVNDAEVER 368

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	41/208 (20%)
eci2	NP_001002645.3	ACBP	39..123	CDD:238248
eci2	NP_001002645.3	crotonase-like	140..387	CDD:329030	48/245 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910