DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG4598 and HADHA

DIOPT Version :9

Sequence 1:NP_001260304.1 Gene:CG4598 / 34315 FlyBaseID:FBgn0032160 Length:281 Species:Drosophila melanogaster
Sequence 2:NP_000173.2 Gene:HADHA / 3030 HGNCID:4801 Length:763 Species:Homo sapiens


Alignment Length:329 Identity:79/329 - (24%)
Similarity:129/329 - (39%) Gaps:84/329 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MMRSKVLSLVARAGSNRMM-----------STATKLTTVEVN--DKTGIATLTMNRP--PVNGLN 50
            |:..:.:.:::|..:.|::           .::..||...:|  .|..:|.:.:|.|  .||.|:
Human     1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLS 65

  Fly    51 LELLQDLKSSIDEI-ESNKSRGLILTSSSSTIFSAGLDILEMYKPDKDRIRAFWTQLQDTWLA-- 112
            .||..:....::|| .|::.|..:|.||....|.||.||        :.:.|..|..:.|.|:  
Human    66 KELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADI--------NMLAACKTLQEVTQLSQE 122

  Fly   113 -------LYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVPN--FTIGLNETQLGIVAPQWFMAS 168
                   |..|:.|..|||||....||..:|.||:||:...:  ..:|..|..||.:..    |.
Human   123 AQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPG----AG 183

  Fly   169 FLSVLPQRIAERA----LNQGRMFTTEEALKVGLIDETAN--------NKEEAIEKCVAFIGTFA 221
            ....||:.:...|    :..||....:.|.|:||:|:...        .:|..||.......|||
Human   184 GTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFA 248

  Fly   222 ------KVNPLARSLTKQQFRAADLQQLQNGRKEDLEKFLF---FVNQPAVQKGLGIYLEGLKKK 277
                  |::|                :...|..|.|..:..   ||.|...:|        :::|
Human   249 KGLADKKISP----------------KRDKGLVEKLTAYAMTIPFVRQQVYKK--------VEEK 289

  Fly   278 AKKQ 281
            .:||
Human   290 VRKQ 293

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG4598NP_001260304.1 crotonase-like 27..217 CDD:119339 59/217 (27%)
HADHANP_000173.2 fa_ox_alpha_mit 27..762 CDD:131494 76/303 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG1024
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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