Protein Alignment CG4598 and HIBCH

DIOPT Version :9

• Sequence 1: NP_001260304.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_055177.2
• Gene: HIBCH / 26275
• HGNCID: 4908
• Length: 386
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 61/308 - (19%)
• Similarity: 114/308 - (37%)
• Gaps: 89/308 - (28%)

  Fly    22 ATKLTTVEVNDKTGIATLTMNRPP-VNGLNLELLQDLKSSIDEIESNKSRGL-ILTSSSSTIFSA 84
            |.:...:|....||:  :|:|||. :|.|.|.:::.:...:.:.|.:....| |:..:....|.|
Human    34 AAEEVLLEKKGCTGV--ITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCA 96

  Fly    85 GLDILEMYKPDKDRIRAFWTQLQDTWL---ALYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVP 146
            |.||..:.:.:|.:.:......::.::   |:.....|..|.|:|.:..||..|:...::||...
Human    97 GGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVATE 161

  Fly   147 NFTIGLNETQLGI--------VAPQ------WFMA------------------------------ 167
            .....:.||.:|:        ..|:      :|:|
Human   162 KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYFLALTGFRLKGRDVYRAGIATHFVDSEKLAMLE 226

  Fly   168 ------------SFLSVLPQRIAERALNQGRMFTTEEALKVGLIDE-----TANNKEEAIEKCVA 215
                        :..|||.....|..:::.:.|..||.:     |:     :||..||.||....
Human   227 EDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHM-----DKINSCFSANTVEEIIENLQQ 286

  Fly   216 FIGTFA--------KVNPLARSLTKQQFRAADLQQLQNGRKEDLEKFL 255
            ...:||        |::|.:..:|        |:||..|..:.|::.|
Human   287 DGSSFALEQLKVINKMSPTSLKIT--------LRQLMEGSSKTLQEVL 326

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	49/255 (19%)
HIBCH	NP_055177.2	PRK05617	34..378	CDD:235533	61/308 (20%)
		ECH_2	47..375	CDD:292731	58/295 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810