Protein Alignment CG4598 and CDY1B

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001003895.1
• Gene: CDY1B / 253175
• HGNCID: 23920
• Length: 554
• Species: Homo sapiens
• Alignment Length: 305
• Identity: 59/305 - (19%)
• Similarity: 109/305 - (35%)
• Gaps: 87/305 - (28%)

  Fly    17 RMMSTATKLTTVEVNDKTGIATLTMNRPPV--NGLNLELLQDLKSSIDEIESNKSRGLILTSSSS 79
            |:..:|:....:.|..:.|...:.::....  |.||.|:::::.::::...::.|: |:|.|::.
Human   275 RLTESASTYRDIVVKKEDGFTQIVLSTRSTEKNALNTEVIKEIVNALNSAAADDSK-LVLFSAAG 338

  Fly    80 TIFSAGLDI---------------LEMYKPDKDRIRAFWTQLQDTWLALYGSSVPTAAAINGHSP 129
            ::|..|||.               |||....|:.:..| .|.:.          |...::||.:.
Human   339 SVFCCGLDFGYFVKHLRNNRNTASLEMVDTIKNFVNTF-IQFKK----------PIVVSVNGPAI 392

  Fly   130 AGGCLLATSCEYRVMVPNFTIGLNETQLGIVAPQWFMASFLS-----------VLPQRIAERALN 183
            ..|..:...|:        .:..||       ..||...:.:           ..|:.:.:.:.|
Human   393 GLGASILPLCD--------LVWANE-------KAWFQTPYTTFGQSPDGCSSITFPKMMGKASAN 442

  Fly   184 Q----GRMFTTEEALKVGLIDETANNKEEAIEKCVAFIGTF-----------AKVNPLARSLTKQ 233
            :    ||..|..||...||:.:            |...|||           |..||:.....|.
Human   443 EMLIAGRKLTAREACAKGLVSQ------------VFLTGTFTQEVMIQIKELASYNPIVLEECKA 495

  Fly   234 QFRA---ADLQQLQNGRKEDLEKFLFFVNQPAVQKGLGIYLEGLK 275
            ..|.   .:|:|......|.|.|  .:.:...::..|.|.|.|.|
Human   496 LVRCNIKLELEQANERECEVLRK--IWSSAQGIESMLKIPLLGYK 538

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	39/221 (18%)
CDY1B	NP_001003895.1	CD_CDY	5..56	CDD:349284
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..106
		crotonase-like	286..482	CDD:119339	42/234 (18%)