Protein Alignment CG4598 and ECHS1

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_004083.3
• Gene: ECHS1 / 1892
• HGNCID: 3151
• Length: 290
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 64/270 - (23%)
• Similarity: 109/270 - (40%)
• Gaps: 34/270 - (12%)

  Fly    30 VNDKTG----IATLTMNRP-PVNGLNLELLQDLKSSIDEIESNKSRGLILTSSSSTIFSAGLDIL 89
            :.:|.|    :..:.:||| .:|.|...|:.:|..::...|.:.:.|.|:.:.....|:||.||.
Human    37 IAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK 101

  Fly    90 EMYKPDKDRIRAFWTQLQDT--------WLALYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVP 146
            ||..          ...||.        |..|.....|..||:||::..|||.||..|:......
Human   102 EMQN----------LSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156

  Fly   147 NFTIGLNETQLGIVAPQWFMASFLSVLPQRIAERALNQGRMFTTEEALKVGLIDETANNK---EE 208
            .......|..:|.:............:.:.:|...:..|...:.::|.:.||:.:....:   ||
Human   157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEE 221

  Fly   209 AIEKCVAFIGTFAKVNPLARSLTKQQFRAADLQQLQNGRKEDLEKFLFFVN--QPAVQKGLGIYL 271
            ||: |...|.:.:|:   ..::.|:...||....|..|.|  |||.||:..  ....::|:..::
Human   222 AIQ-CAEKIASNSKI---VVAMAKESVNAAFEMTLTEGSK--LEKKLFYSTFATDDRKEGMTAFV 280

  Fly   272 EGLKKKAKKQ 281
            |..|...|.|
Human   281 EKRKANFKDQ 290

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	46/202 (23%)
ECHS1	NP_004083.3	crotonase-like	32..288	CDD:474030	62/266 (23%)