DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4598 and ech-1.1

DIOPT Version :9

Sequence 1:	NP_001260304.1	Gene:	CG4598 / 34315	FlyBaseID:	FBgn0032160	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_506810.1	Gene:	ech-1.1 / 180037	WormBaseID:	WBGene00001150	Length:	755	Species:	Caenorhabditis elegans

Alignment Length:	238	Identity:	59/238 - (24%)
Similarity:	103/238 - (43%)	Gaps:	37/238 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 TTVEVNDKTGIATLTMNRPPV--NGLNLELLQDLKSSIDEIESNKS-RGLILTSSSSTIFSAGLD 87
            :|..|..:..:|.:.::.|..  |.||..|..::..::|.::|::| :.:::.|.....|.||.|
Worm    31 STHRVEKQGDVAVMKIDLPNTTENVLNKALFAEMNETLDRLQSDQSVKAIVVMSGKPNSFVAGAD 95

  Fly    88 ILEMYKPDK------DRIRAFWTQLQDTWLALYGSSVPTAAAINGHSPAGGCLLATSCEYRVMV- 145
            | :|:|.:|      :.:|....||    |.:..|..|..|||.|....||..:|.:|.||:.|
Worm    96 I-QMFKAEKTAAGVSNLLREGQKQL----LTIELSQKPIVAAIMGSCMGGGLEIALACHYRIAVN 155

  Fly   146 -PNFTIGLNETQLGIVAPQWFMASFLSVLP-----QRIAERALNQGRMFTTEEALKVGLIDETAN 204
             ....:||.|..|||:...    .....||     |.:.:..|. |:.....:|:|:|::|....
Worm   156 DKKTLLGLPEVTLGIMPGD----GGTQRLPKLTTVQNVLDLTLT-GKRIKANKAMKIGIVDRVIQ 215

  Fly   205 NKEEAIEKCVAFIGTFAKVNPLARSLTKQQFRAADLQQLQNGR 247
            ...:.|  |.:...|...:..:|         ....::|.||:
Worm   216 PLGDGI--CTSTETTHKYLEEIA---------VQSARELANGK 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	54/205 (26%)
ech-1.1	NP_506810.1	fa_ox_alpha_mit	20..754	CDD:131494	59/238 (25%)
		crotonase-like	34..216	CDD:119339	51/191 (27%)
		3HCDH_N	355..533	CDD:280833
		3HCDH	535..630	CDD:279114
		3HCDH	668..754	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810