DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4598 and ech-4

DIOPT Version :9

Sequence 1:	NP_001260304.1	Gene:	CG4598 / 34315	FlyBaseID:	FBgn0032160	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_001366707.1	Gene:	ech-4 / 174665	WormBaseID:	WBGene00001153	Length:	385	Species:	Caenorhabditis elegans

Alignment Length:	239	Identity:	50/239 - (20%)
Similarity:	93/239 - (38%)	Gaps:	61/239 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    39 LTMNRP-PVNGLNLELLQDLKSSIDEIESNKSRGLILTSSSSTIFSAGLDILEMYKP----DKDR 98
            :.:||| ..|.|.||:.|.::.:::...::||..:.:.:::.:.:.||.| |..:|.    .|::
Worm   140 IALNRPKKFNALTLEMYQGIQKALEVSNNDKSTSITVITANGSYYCAGND-LTNFKAAAGGTKEQ 203

  Fly    99 IRAFWTQ----LQDTWLALYGSSVPTAAAINGHSPAGGCLLATSCEYRVMVPNFTIGLNETQLG- 158
            |......    ::|...|......|..|.|||  ||                   :|:..|.||
Worm   204 IADMANTAKVIMKDYVNAYINHEKPLIALING--PA-------------------VGIAVTVLGM 247

  Fly   159 ---IVAPQWFMASF------LSVLPQRI-------------AERALNQGRMFTTEEALKVGLIDE 201
               ::|..  .|||      |...|:.:             |...|...:..:.:.|...||::|
Worm   248 FDYVIATD--KASFHTPFAPLGQSPEGVSSYTFPLIMGSLRASEMLLVCKKISAQTAKDYGLVNE 310

  Fly   202 TANNKE--EAIEKCVAFIGTFAKVNPLARSLTKQQFRAADLQQL 243
            ...:.|  ...:|.|.   .|:::.|....:.|:..|:...::|
Worm   311 VVPDAEFQSHAQKTVE---AFSQLPPETLRINKKLLRSLHKEKL 351

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	45/211 (21%)
ech-4	NP_001366707.1	ACBP	25..109	CDD:238248
ech-4	NP_001366707.1	crotonase-like	129..326	CDD:119339	44/209 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1024
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810