DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG4598 and ech-1.2

DIOPT Version :9

Sequence 1:	NP_001260304.1	Gene:	CG4598 / 34315	FlyBaseID:	FBgn0032160	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	NP_491789.1	Gene:	ech-1.2 / 172310	WormBaseID:	WBGene00020347	Length:	781	Species:	Caenorhabditis elegans

Alignment Length:	307	Identity:	70/307 - (22%)
Similarity:	127/307 - (41%)	Gaps:	48/307 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RSKVLSLVARAGSNRM----------MSTATKLTTVEVNDKTGIATLTMNRPPV--NGLNLELLQ 55
            :.::||.:....|:.:          .|.....||..|..:..:|.:.::.|..  |.||..|..
Worm    24 QKEMLSRLVHQSSSTLRTNLSFRLFSQSAPAMQTTHRVEKQGDVAVVKIDLPNTKENVLNKALFA 88

  Fly    56 DLKSSIDEIESNKS-RGLILTSSSSTIFSAGLDILEMYKPD--KDRIRAFWTQLQDTWLALYGSS 117
            ::|:::|:::|::| :.:::.|.....|.||.|| :|.|.:  .........:.|:.:..:..|.
Worm    89 EMKATLDKLQSDESIKSIVVMSGKPNSFVAGADI-QMIKAEGTATATETLSREGQEQFFRIEKSQ 152

  Fly   118 VPTAAAINGHSPAGGCLLATSCEYRVMV--PNFTIGLNETQLGIVAPQWFMASFLSVLP-----Q 175
            .|..|||.|....||..||.:|.||:.|  ....:.|.|..||::..    |.....||     |
Worm   153 KPVVAAIMGSCMGGGLELALACHYRIAVNDKKTLLSLPEVMLGLLPG----AGGTQRLPKLTTVQ 213

  Fly   176 RIAERALNQGRMFTTEEALKVGLIDETANNKEEAIEKCVAFIGTFAKVNPLARSLTK--QQFRAA 238
            .:.:..|. |:....::|.|:|::|.......:.:             .|.|.:..|  ::....
Worm   214 NVLDLTLT-GKKIKADKAKKIGIVDRVIQPLGDGL-------------GPAAENTHKYLEEIAVK 264

  Fly   239 DLQQLQNGR-KEDLEK-FLFFVNQPAVQKGL---GIYLEGLKKKAKK 280
            ..|:|.||: |.:.:| |:....|..:...|   .:.|:..|.|..|
Worm   265 AAQELANGKLKINRDKGFMHKATQAVMTNSLFLDNVVLKMAKDKLMK 311

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_001260304.1	crotonase-like	27..217	CDD:119339	49/201 (24%)
ech-1.2	NP_491789.1	fa_ox_alpha_mit	46..780	CDD:131494	67/285 (24%)
		crotonase-like	60..269	CDD:119339	52/227 (23%)
		3HCDH_N	381..559	CDD:280833
		3HCDH	561..656	CDD:279114
		3HCDH	694..780	CDD:279114
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910