Protein Alignment CG4598 and ECI1

DIOPT Version :10

• Sequence 1: NP_609322.1
• Gene: CG4598 / 34315
• FlyBaseID: FBgn0032160
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_001910.2
• Gene: ECI1 / 1632
• HGNCID: 2703
• Length: 302
• Species: Homo sapiens
• Alignment Length: 270
• Identity: 107/270 - (39%)
• Similarity: 162/270 - (60%)
• Gaps: 14/270 - (5%)

  Fly    12 RAGSNRMMSTATKLTTVEVNDKTGIATLTMNRPPVNGLNLELLQDLKSSIDEIESNKS-RGLILT 75
            |.||.|::        ||.:...|:|.:....||||.|:||.|.:|..|::::|::|| ||:|||
Human    41 RFGSQRVL--------VEPDAGAGVAVMKFKNPPVNSLSLEFLTELVISLEKLENDKSFRGVILT 97

  Fly    76 SSSSTIFSAGLDILEMYKPDKDRIRAFWTQLQDTWLALYGSSVPTAAAINGHSPAGGCLLATSCE 140
            |....:||||||:.||..........:|..:|:.||.||.|::...:||||..||||||:|.:|:
Human    98 SDRPGVFSAGLDLTEMCGRSPAHYAGYWKAVQELWLRLYQSNLVLVSAINGACPAGGCLVALTCD 162

  Fly   141 YRVMV--PNFTIGLNETQLGIVAPQWFMASFLSVLPQRIAERALNQGRMFTTEEALKVGLIDETA 203
            ||::.  |.:.||||||||||:||.|...:..:.:..|.|||||..|.:|...|||:||::|:..
Human   163 YRILADNPRYCIGLNETQLGIIAPFWLKDTLENTIGHRAAERALQLGLLFPPAEALQVGIVDQVV 227

  Fly   204 NNKEEAIEK-CVAFIGTFAKVNPLARSLTKQQFRAADLQQLQNGRKEDLEKFLFFVNQPAVQKGL 267
              .||.::. .::.|..:..:...||.|||...|.|...:|...|..|::.|:.|:::.::||.|
Human   228 --PEEQVQSTALSAIAQWMAIPDHARQLTKAMMRKATASRLVTQRDADVQNFVSFISKDSIQKSL 290

  Fly   268 GIYLEGLKKK 277
            .:|||.||::
Human   291 QMYLERLKEE 300

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4598	NP_609322.1	crotonase-like	27..217	CDD:119339	82/193 (42%)
ECI1	NP_001910.2	ECH_1	52..298	CDD:395302	99/247 (40%)