DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG5885 and SSR3

DIOPT Version :9

Sequence 1:	NP_001303317.1	Gene:	CG5885 / 34314	FlyBaseID:	FBgn0025700	Length:	190	Species:	Drosophila melanogaster
Sequence 2:	NP_001295126.1	Gene:	SSR3 / 6747	HGNCID:	11325	Length:	198	Species:	Homo sapiens

Alignment Length:	202	Identity:	118/202 - (58%)
Similarity:	152/202 - (75%)	Gaps:	23/202 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 GSGKQQKVQSSGFTKEEELLLQDFSRNVSTKSSALFYGNAFIVSAVPIWLFWRIHNMDLWPSSIL 66
            ||.|||        .||:|||||||||:|.||||||:||||||||:||||:|||.:|||..|::|
Human     5 GSSKQQ--------SEEDLLLQDFSRNLSAKSSALFFGNAFIVSAIPIWLYWRIWHMDLIQSAVL 61

  Fly    67 FVLVTAASTYLMATAYKNIKFQLKHKIAGRREEAVTREVNRQV--GDDKKVTRKEKDER------ 123
            :.::|..||||:|.||||:||.||||:|.:||:||::||.|::  .|::|::|||||||
Human    62 YSVMTLVSTYLVAFAYKNVKFVLKHKVAQKREDAVSKEVTRKLSEADNRKMSRKEKDERFDSCLK 126

  Fly   124 -------ILWKKNEVADYEATTFSIFYNNAIYLAVIIFISFFILKNSTPFINYIFSVGIASGALS 181
                   ||||||||||||||||||||||.::|.|:|..|||||||..|.:|||.|:..:||.::
Human   127 YGHHKRGILWKKNEVADYEATTFSIFYNNTLFLVVVIVASFFILKNFNPTVNYILSISASSGLIA 191

  Fly   182 LFSTSAQ 188
            |.||.::
Human   192 LLSTGSK 198

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG5885	NP_001303317.1	TRAP-gamma	17..186	CDD:284484	112/183 (61%)
SSR3	NP_001295126.1	TRAP-gamma	12..196	CDD:311185	112/183 (61%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165140808
Domainoid	1	1.000	235	1.000	Domainoid score	I2367
eggNOG	1	0.900	-	-		E1_KOG4490
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H5154
Inparanoid	1	1.050	238	1.000	Inparanoid score	I3368
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55882
OrthoDB	1	1.010	-	-		D1450535at2759
OrthoFinder	1	1.000	-	-		FOG0006475
OrthoInspector	1	1.000	-	-		oto88717
orthoMCL	1	0.900	-	-		OOG6_107048
Panther	1	1.100	-	-	LDO	PTHR13399
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4190
SonicParanoid	1	1.000	-	-		X5447
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800