DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yip2 and acat2

DIOPT Version :9

Sequence 1:	NP_523528.1	Gene:	yip2 / 34313	FlyBaseID:	FBgn0040064	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_988965.1	Gene:	acat2 / 394562	XenbaseID:	XB-GENE-5929870	Length:	398	Species:	Xenopus tropicalis

Alignment Length:	399	Identity:	161/399 - (40%)
Similarity:	238/399 - (59%)	Gaps:	7/399 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAATKGIYIVAAKRTAFGTFGGSLKGINQTQLQTTAAKAALDAAGLKGEQVDTVIVGNVIASSS 65
            ||:..:.:.||:|.||..|:|.|:|..:....|.:|..|..|..|.::.::|..||.|.|:.:.:
Frog     1 MSSREERVAIVSAARTPIGSFNGALSTLPAHTLGSTVIKEVLKRAAIQPQEVSEVIFGQVLTAGA 65

  Fly    66 TDGIYVPRHVGLNCGVPIEKPALGINRLCGSGFQSIVNGAQDILVGGAKIALTGGVENMSQSPFI 130
              |....|...:..|||...||.....:||||.:::..|||.|..|.|.|.:.||:|:|||:|.:
Frog    66 --GQNPARQASVAAGVPYSIPAWSCQMICGSGLKAVSLGAQSIKTGEADIVVAGGMESMSQAPHL 128

  Fly   131 ARNVRFGTTLGASYNLEDALWA-GLTDTYCKLPMALTAENLADQYKISRERVDEFSLLSQKNWEK 194
            . ::|.|...| ..:|:|::.. ||.|.:.|..|.:||||:|.|:|::||..|..::.||...|.
Frog   129 V-HMRAGVKAG-DVSLQDSIMCDGLNDAFYKYHMGITAENVAKQWKVTREEQDLLAVQSQNRTEA 191

  Fly   195 GQKEGAFNAEITPIKLKVKGKEVDFVVDEHPRPKTTIEGLNKLPSLFKK--NGVVTAGTASGICD 257
            .||.|.|:.||.|:.:..:...|:..|||.||..:.:|.::||...|.|  :|.||...||||.|
Frog   192 AQKAGYFDKEIVPVTVPSRKGPVEVKVDEFPRHGSNVEAMSKLKPYFLKDGSGTVTPANASGIND 256

  Fly   258 GASAVIVASEEALKEYNLKPLARLVAFSFVGVKPEIMGIGPVPAIQNVLKVSGKKLEDIDLIEIN 322
            ||:|||:..|...:...|.|:|.:|:.:.||:.|.|||:||:.||:..::.:|..|:::||.|||
Frog   257 GAAAVILIKESEARRRGLVPMAHIVSSAQVGLDPSIMGVGPIAAIRKAVEKAGWSLDEVDLFEIN 321

  Fly   323 EAFAAQTLACADALKLDTSKLNVNGGAIALGHPLGASGSRITGHLVHELQRKKLKYGIGSACIGG 387
            ||||||.:|....|.|:..|:|..|||:|||||||.||.||...|::.|:|...|.|:.:.||||
Frog   322 EAFAAQAVAVVKDLGLNPEKVNCQGGAVALGHPLGMSGCRILVTLLYALERTGGKKGVAALCIGG 386

  Fly   388 GQGIALLLE 396
            |.|||:.:|
Frog   387 GMGIAMCIE 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yip2	NP_523528.1	PRK05790	6..398	CDD:180261	159/394 (40%)
yip2	NP_523528.1	thiolase	9..397	CDD:238383	159/391 (41%)
acat2	NP_988965.1	PRK05790	6..396	CDD:180261	159/394 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	1	1.000	-	-		FOG0000432
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920