DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yip2 and Acat2

DIOPT Version :9

Sequence 1:	NP_523528.1	Gene:	yip2 / 34313	FlyBaseID:	FBgn0040064	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_001006996.1	Gene:	Acat2 / 308100	RGDID:	1359366	Length:	397	Species:	Rattus norvegicus

Alignment Length:	398	Identity:	158/398 - (39%)
Similarity:	240/398 - (60%)	Gaps:	5/398 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSAATKGIYIVAAKRTAFGTFGGSLKGINQTQLQTTAAKAALDAAGLKGEQVDTVIVGNVIASSS 65
            |:|.:..:.|::|.|||.|:|.|:|..:....|.||..|..|..|.:..|:|..||.|:|:.:..
  Rat     1 MNAGSDPVVIISAARTAIGSFNGALSTVPVHNLGTTVIKEVLQRAKVAPEEVSEVIFGHVLTAGC 65

  Fly    66 TDGIYVPRHVGLNCGVPIEKPALGINRLCGSGFQSIVNGAQDILVGGAKIALTGGVENMSQSPFI 130
              |....|...:..|:|...||.....:||||.:::...||.|.:|.:.|.:.||:||||::|.:
  Rat    66 --GQNPTRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAAQSIAMGDSTIVVAGGMENMSKAPHL 128

  Fly   131 ARNVRFGTTLGASYNLEDALWAGLTDTYCKLPMALTAENLADQYKISRERVDEFSLLSQKNWEKG 195
            | ::|.|..:|.....:..|..||||.:....|.:||||:|.::::|||..|:.:::||...|..
  Rat   129 A-HLRSGVKMGEVPLADSILCDGLTDAFHNYHMGITAENVAKKWQVSREAQDKVAVVSQNRAEHA 192

  Fly   196 QKEGAFNAEITPIKLKVKGKEVDFVVDEHPRPKTTIEGLNKLPSLFKKN--GVVTAGTASGICDG 258
            ||.|.|:.||.|:.:..:....:..:||.||..:.:|.::||...|..:  |.||...|||:.||
  Rat   193 QKAGHFDKEIVPVHVSSRKGLTEVKIDEFPRHGSNLEAMSKLKPYFLTDGTGTVTPANASGMNDG 257

  Fly   259 ASAVIVASEEALKEYNLKPLARLVAFSFVGVKPEIMGIGPVPAIQNVLKVSGKKLEDIDLIEINE 323
            |:||::..:...:...|||||::|::|..||:|.:||:||:|||:..:..:|..|||:|:.||||
  Rat   258 AAAVVLMKKTEAESRMLKPLAQVVSWSQAGVEPSVMGVGPIPAIKQAVAKAGWSLEDVDVFEINE 322

  Fly   324 AFAAQTLACADALKLDTSKLNVNGGAIALGHPLGASGSRITGHLVHELQRKKLKYGIGSACIGGG 388
            ||||.:.|.|..|.|...|:|::||||||||||||||.||...|:|.|:|.....|:.:.|||||
  Rat   323 AFAAVSAAIAKELGLSPEKVNIDGGAIALGHPLGASGCRILVTLLHTLERVGGTRGVAALCIGGG 387

  Fly   389 QGIALLLE 396
            .|||:.::
  Rat   388 MGIAMCVQ 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yip2	NP_523528.1	PRK05790	6..398	CDD:180261	156/393 (40%)
yip2	NP_523528.1	thiolase	9..397	CDD:238383	156/390 (40%)
Acat2	NP_001006996.1	PRK05790	8..396	CDD:180261	156/391 (40%)
Acat2	NP_001006996.1	thiolase	9..396	CDD:238383	156/390 (40%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	1	1.000	-	-		FOG0000432
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.920