DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment yip2 and Acaa2

DIOPT Version :9

Sequence 1:	NP_523528.1	Gene:	yip2 / 34313	FlyBaseID:	FBgn0040064	Length:	398	Species:	Drosophila melanogaster
Sequence 2:	NP_569117.2	Gene:	Acaa2 / 170465	RGDID:	620482	Length:	397	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	231/394 - (58%)
Similarity:	285/394 - (72%)	Gaps:	1/394 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 AATKGIYIVAAKRTAFGTFGGSLKGINQTQLQTTAAKAALDAAGLKGEQVDTVIVGNVIASSSTD 67
            |..:|::|||||||.||.:||.||....|.|...||:|||.|..:..|.:|:||||||:.||| |
  Rat     2 ALLRGVFIVAAKRTPFGAYGGLLKDFTATDLTEFAARAALSAGKVPPETIDSVIVGNVMQSSS-D 65

  Fly    68 GIYVPRHVGLNCGVPIEKPALGINRLCGSGFQSIVNGAQDILVGGAKIALTGGVENMSQSPFIAR 132
            ..|:.|||||..|||.|..||.:||||||||||||:|.|:|....|::.|.||.|:|||||:..|
  Rat    66 AAYLARHVGLRVGVPTETGALTLNRLCGSGFQSIVSGCQEICSKDAEVVLCGGTESMSQSPYSVR 130

  Fly   133 NVRFGTTLGASYNLEDALWAGLTDTYCKLPMALTAENLADQYKISRERVDEFSLLSQKNWEKGQK 197
            ||||||..|....|||.|||||||.:.||||.:||||||.:|.||||..|.::|.||:.|:...:
  Rat   131 NVRFGTKFGLDLKLEDTLWAGLTDQHVKLPMGMTAENLAAKYNISREDCDRYALQSQQRWKAANE 195

  Fly   198 EGAFNAEITPIKLKVKGKEVDFVVDEHPRPKTTIEGLNKLPSLFKKNGVVTAGTASGICDGASAV 262
            .|.||.|:.||::|.|..:....||||.||:||:|.|.|||.:|||.|.||||.|||:.|||..|
  Rat   196 AGYFNEEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVFKKEGTVTAGNASGMSDGAGVV 260

  Fly   263 IVASEEALKEYNLKPLARLVAFSFVGVKPEIMGIGPVPAIQNVLKVSGKKLEDIDLIEINEAFAA 327
            |:|||:|:|::|..||||:|.:...|..|.||||||||||...||.:|..|:|:|||::|||||.
  Rat   261 IIASEDAVKKHNFTPLARVVGYFVSGCDPAIMGIGPVPAITGALKKAGLSLKDMDLIDVNEAFAP 325

  Fly   328 QTLACADALKLDTSKLNVNGGAIALGHPLGASGSRITGHLVHELQRKKLKYGIGSACIGGGQGIA 392
            |.||...:|.||.||.||:|||||||||||.||||||.||||||:|:..||.:|||||||||||:
  Rat   326 QFLAVQKSLDLDPSKTNVSGGAIALGHPLGGSGSRITAHLVHELRRRGGKYAVGSACIGGGQGIS 390

  Fly   393 LLLE 396
            |:::
  Rat   391 LIIQ 394

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
yip2	NP_523528.1	PRK05790	6..398	CDD:180261	230/391 (59%)
yip2	NP_523528.1	thiolase	9..397	CDD:238383	229/388 (59%)
Acaa2	NP_569117.2	thiolase	8..395	CDD:238383	229/388 (59%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166340540
Domainoid	1	1.000	285	1.000	Domainoid score	I1548
eggNOG	1	0.900	-	-		E1_COG0183
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4456
Inparanoid	1	1.050	450	1.000	Inparanoid score	I1564
OMA	1	1.010	-	-		QHG58994
OrthoDB	1	1.010	-	-		D1129049at2759
OrthoFinder	1	1.000	-	-		FOG0000432
OrthoInspector	1	1.000	-	-		oto96620
orthoMCL	1	0.900	-	-		OOG6_104226
Panther	1	1.100	-	-	LDO	PTHR18919
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X5028
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.770