Protein Alignment Srp54 and Srsf11

DIOPT Version :9

• Sequence 1: NP_477347.1
• Gene: Srp54 / 34312
• FlyBaseID: FBgn0024285
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_001366460.1
• Gene: Srsf11 / 69207
• MGIID: 1916457
• Length: 518
• Species: Mus musculus
• Alignment Length: 561
• Identity: 191/561 - (34%)
• Similarity: 255/561 - (45%)
• Gaps: 151/561 - (26%)

  Fly     3 GGNTPRVIQVTNIAPQATKDQMQTLFGNIGKIEEIRLYPTIRDVSCPVQSRICYVKYTDTTSVPV 67
            ||.| .||||||::|.|:.:||:||||.:|||:|:||:|. .|...||.||:|:||:.|..|..|
Mouse    57 GGGT-EVIQVTNVSPSASSEQMRTLFGFLGKIDELRLFPP-DDSPLPVSSRVCFVKFHDPDSAVV 119

  Fly    68 AQHLTNTVFIDRALIVIPVL--AIPEEYRALEMLKNGTIVPGLQKPDSKLP-PEVINRIEGQLPQ 129
            |||||||||:||||||:|..  .||:|.:||.:|.....|.||......|| |..:.:| |.:|.
Mouse   120 AQHLTNTVFVDRALIVVPYAEGVIPDETKALSLLAPANAVAGLLPGGGLLPTPNPLTQI-GAVPL 183

  Fly   130 QVI--KTYDPKLVEFNLPEYPALPSFYDARKIEEIRRTIIVCDVKNEWRLDDLMECFQRAGEVKY 192
            ..:  ...||.|....||..........|.::.::..|:
Mouse   184 AALGAPALDPALAALGLPGTNLNSQSLAADQLLKLMSTV-------------------------- 222

  Fly   193 ARWAEKDNKTYCMIEFCEQTSIIHALRMQGQEFKGGHLSVYHSTYSITKPEAKSNEAAQAEIEEA 257
                  |.|                              :.|....:..|..||:.::: |||||
Mouse   223 ------DPK------------------------------LNHVAAGLVSPSLKSDTSSK-EIEEA 250

  Fly   258 MTIVKEAQSMISAAIDPVIGMLAKDKRRRSRSRSRSRDRRT---SRSRSHRSTSRRRS------- 312
            |..|:||||:|||||:|   ...::|||.||||||||.|||   ||.|..||.|||||
Mouse   251 MKRVREAQSLISAAIEP---DKKEEKRRHSRSRSRSRRRRTPSSSRHRRSRSRSRRRSHSKSRSR 312

  Fly   313 RRSGS-RERRSVSRSRRSRSRGKHSSRSRSKRSRSRHR-----RSSSRSRRSRSRGGKHSRSSRS 371
            |||.| |.|||.||.|..|||....:|.:.|..:.:.|     :|.|.:|||||....|...||.
Mouse   313 RRSKSPRRRRSHSRERGRRSRSTSKARDKKKEDKEKKRSKTPPKSYSTARRSRSASSLHVCDSRE 377

  Fly   372 RGKRSRSRHRRSTSRSRSSRSHGTGGGGSGNGKRSRSRERSKKSHRSEKHSSR-SPRSRSKRSSP 435
            |      |.|||.|.:||.:.       ..:.||..||..|.:.|:.||...: ..|||.:|..
Mouse   378 R------RRRRSRSGTRSPKK-------PRSPKRKLSRSPSPRRHKKEKKKDKDKERSRDERER- 428

  Fly   436 SPPPATGSKSRSSRSKDPVIVSAKSSRRRDRSRTPETRK-LKSISED-----------TEVKSSR 488
                   |.|:..||||         :.::|.|..|:.| :|.::.|           .|.|..:
Mouse   429 -------STSKKKRSKD---------KEKERERKSESDKDVKQVTRDYDEEEQGYDSEKEKKEEK 477

  Fly   489 --SSADSKSRKSVSVEK----------------SDNMDISN 511
              :.|.|...|..||||                .::||:|:
Mouse   478 RPTEAVSPKTKECSVEKGVGDLRESKVNGDDHHEEDMDMSD 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp54	NP_477347.1	RRM_SRSF11_SREK1	9..85	CDD:240705	47/75 (63%)
		RRM2_SREK1	160..242	CDD:240706	4/81 (5%)
Srsf11	NP_001366460.1	RRM_SRSF11	62..141	CDD:409940	48/79 (61%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167837904
Domainoid	1	1.000	69	1.000	Domainoid score	I9621
eggNOG	1	0.900	-	-		E1_KOG4676
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45943
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003613
OrthoInspector	1	1.000	-	-		oto92236
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR32343
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5511
SonicParanoid	1	1.000	-	-		X2488
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930