Protein Alignment Srp54 and srsf11

DIOPT Version :9

• Sequence 1: NP_477347.1
• Gene: Srp54 / 34312
• FlyBaseID: FBgn0024285
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: XP_004913979.1
• Gene: srsf11 / 549632
• XenbaseID: XB-GENE-1016408
• Length: 534
• Species: Xenopus tropicalis
• Alignment Length: 568
• Identity: 175/568 - (30%)
• Similarity: 241/568 - (42%)
• Gaps: 177/568 - (31%)

  Fly     9 VIQVTNIAPQATKDQMQTLFGNIGKIEEIRLYPTIRDVSCPVQSRICYVKYTDTTSVPVAQHLTN 73
            ||||||::|.|:.:||:||||.:|||||:||:|. .|...||.||:|:||:.|..|..|||||||
 Frog     7 VIQVTNVSPSASSEQMKTLFGFLGKIEELRLFPP-DDSPLPVTSRVCFVKFQDPDSAVVAQHLTN 70

  Fly    74 TVFIDRALIVIPVL--AIPEEYRALEMLKNGTIVPGLQKPDSKLP-PEVINRIEGQLPQQVI--K 133
            |||:||||||:|..  .||:|.:||.::.....|.||......|| |..:::| |.:|...:  .
 Frog    71 TVFVDRALIVVPYAEGIIPDEAKALSLVAPANAVAGLLPGGGLLPTPNPLSQI-GAVPLAALGAP 134

  Fly   134 TYDPKLVEFNLPEYPALPSFYDARKIEEIRRTIIVCDVKNEWRLDDLMECFQRAGEVKYARWAEK 198
            |.||.|....||..........|.::.::..|:
 Frog   135 TLDPTLAALTLPGANLNSQSLAADQLLKLMSTV-------------------------------- 167

  Fly   199 DNKTYCMIEFCEQTSIIHALRMQGQEFKGGHLSVYHSTYSITKPEAKSNEAAQAEIEEAMTIVKE 263
            |.|                              :.|.|..:..|..||:.::: :|||||..|:|
 Frog   168 DPK------------------------------LNHVTAGLVSPSLKSDTSSK-DIEEAMKRVRE 201

  Fly   264 AQSMISAAIDPVIGMLAKDKRRRSRSRSRSRDRRTSRSRSHRSTSRRRSRRSGSRERRSVSRSRR 328
            |||:|||||:|       ||:       ..:.::.||||||   ||||...|.||.|||.|||||
 Frog   202 AQSLISAAIEP-------DKK-------DEKSKKHSRSRSH---SRRRRTPSSSRHRRSRSRSRR 249

  Fly   329 SRSRGKHSSRSRSKRSRSRHRRSSSRSRRSRSRGGK----------HSRSSR------------- 370
             ||..|..||.|||..|.|...|..|||||||....          |:.:::
 Frog   250 -RSHSKSRSRRRSKSPRRRRSHSRERSRRSRSTSKPRFFFLFFFTYHNCNTKKCPVLVVCDFYQY 313

  Fly   371 --------------------------SRGK------------------RSRSRHRRSTSRSRS-S 390
                                      :.|.                  |.:.|..:...||:: .
 Frog   314 RATVHNILITLIYITQFMVLLFLFLFNYGSYYIFHVFVASLNLLLVFFREKKREEKEKKRSKTPP 378

  Fly   391 RSHGTGGGGSGNGKRSRSRERSKKSHRSEKHSSRSP---RSRSKRSSPSPPPATGSKSRSSRSKD 452
            :|:.|       .:||||..|.|: .|..:..||||   ||..::.|.||.|....|.: .:.||
 Frog   379 KSYST-------TRRSRSTSRDKR-RRKSRSGSRSPKKLRSPKRKPSRSPSPRRHKKEK-KKDKD 434

  Fly   453 PVIVSAKSSRRRDRSRTPETRKLKSISEDTEVKSSRSSADSKSRKSVS 500
                  :...|.:|.|:...:|.   |:|.|.:..|.|...|..|.|:
 Frog   435 ------REKNRDERERSSSKKKK---SKDKEKERERRSESEKDVKQVT 473

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp54	NP_477347.1	RRM_SRSF11_SREK1	9..85	CDD:240705	48/75 (64%)
		RRM2_SREK1	160..242	CDD:240706	5/81 (6%)
srsf11	XP_004913979.1	RRM_SRSF11	7..86	CDD:240962	49/79 (62%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	70	1.000	Domainoid score	I9387
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	247	1.000	Inparanoid score	I3189
OMA	1	1.010	-	-		QHG45943
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003613
OrthoInspector	1	1.000	-	-		otm47678
Panther	1	1.100	-	-	O	PTHR32343
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5511
SonicParanoid	1	1.000	-	-		X2488
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	8.190