Protein Alignment Srp54 and srsf11

DIOPT Version :9

• Sequence 1: NP_477347.1
• Gene: Srp54 / 34312
• FlyBaseID: FBgn0024285
• Length: 513
• Species: Drosophila melanogaster
• Sequence 2: NP_955870.1
• Gene: srsf11 / 321886
• ZFINID: ZDB-GENE-030131-605
• Length: 461
• Species: Danio rerio
• Alignment Length: 522
• Identity: 189/522 - (36%)
• Similarity: 252/522 - (48%)
• Gaps: 119/522 - (22%)

  Fly     9 VIQVTNIAPQATKDQMQTLFGNIGKIEEIRLYPTIRDVSCPVQSRICYVKYTDTTSVPVAQHLTN 73
            ||||||::|.:|.:||:||||.||.|:|:||:|. .|...||.||:|:||:.:..||.|:|||||
Zfish     8 VIQVTNVSPSSTAEQMRTLFGFIGSIDELRLFPP-DDSPLPVTSRVCFVKFHEPESVGVSQHLTN 71

  Fly    74 TVFIDRALIVIPVL--AIPEEYRALEMLKNGTIVPGLQKPDSKLP-PEVINRIEGQLPQQVIKTY 135
            |||:||||||:|..  .||:|.:|:.:|.....|.||......|| |..:..| |.:|...:.
Zfish    72 TVFVDRALIVVPFAEGVIPDESKAMSLLAPANAVAGLLPGGGLLPTPNPVPSI-GGVPLGGLG-- 133

  Fly   136 DPKLVEFNLPEYPAL--------PSFYDARKIEEIRRTIIVCDVKNEWRLDDLMECFQRAGEVKY 192
            .|     ||....||        |....|.::.::..:|
Zfish   134 GP-----NLDPMAALAMAAPNINPQSLSAEQLMKLMASI-------------------------- 167

  Fly   193 ARWAEKDNKTYCMIEFCEQTSIIHALRMQGQEFKGGHLSVYHSTYSITKPEAKSNEAAQAEIEEA 257
                  |.|                            |:...:..::| |..|: :|:..|||||
Zfish   168 ------DPK----------------------------LNPLAAGLNLT-PGLKA-DASNKEIEEA 196

  Fly   258 MTIVKEAQSMISAAIDPVIGMLAKDKRRRSRSRSRSRDRRT-SRSRSHRSTSRRRSRRSGSRERR 321
            |..|:||||:|||||:|  |....|||:|||||||||.||: ||||..||.|..| |||.||.||
Zfish   197 MKRVREAQSLISAAIEP--GSKKDDKRKRSRSRSRSRRRRSRSRSRHRRSKSHSR-RRSRSRSRR 258

  Fly   322 SVSRSRRSRSRGKHSSRSRSKRSRSRHRRSSSRSR-RSRSRGGKHSRSSRSRGKRSRSRHRRSTS 385
               ||:..|.|..| ||.||:|||||.||...:.| ||::....:|.:.||| ..||.|||||.|
Zfish   259 ---RSKSPRRRRSH-SRDRSRRSRSRDRRKDEKYRKRSKTPPKSYSSARRSR-STSRKRHRRSRS 318

  Fly   386 RSRSSRSHGTGGGGSGNGKRSRSRERSKKSHRSEKHSSRS---PRSRSKRSSPSPPPATGSKSRS 447
            .|||.:.       |.:.||..||..|.:.|:.||...:.   .|.|.::...........:|.|
Zfish   319 MSRSPKK-------SRSPKRKLSRSPSPRRHKKEKKKDKDRERDRDRDRKEDRDRNREKRERSTS 376

  Fly   448 SRSKDPVIVSAKSSRRRDRSRTPETRKLKSISEDTEVKSSRS-SADSKSRKSVSVEKSDNMDISN 511
            .:|||         :.:||.|       ||.||..:||.:|. ..:.:...|...|...|.|.::
Zfish   377 KKSKD---------KDKDRDR-------KSDSEKGDVKVTRDYDEEEQGYDSEHEEHERNSDAAS 425

  Fly   512 SP 513
            ||
Zfish   426 SP 427

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Srp54	NP_477347.1	RRM_SRSF11_SREK1	9..85	CDD:240705	46/75 (61%)
		RRM2_SREK1	160..242	CDD:240706	5/81 (6%)
srsf11	NP_955870.1	RRM_SRSF11	8..87	CDD:240962	47/79 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170581693
Domainoid	1	1.000	179	1.000	Domainoid score	I3508
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	246	1.000	Inparanoid score	I3259
OMA	1	1.010	-	-		QHG45943
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003613
OrthoInspector	1	1.000	-	-		otm26485
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2488
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	6.990