Protein Alignment Etl1 and Smarca5

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_444354.2
• Gene: Smarca5 / 93762
• MGIID: 1935129
• Length: 1051
• Species: Mus musculus
• Alignment Length: 724
• Identity: 226/724 - (31%)
• Similarity: 355/724 - (49%)
• Gaps: 139/724 - (19%)

  Fly   130 PLAKSKLKPRSNGISGGNFSDNDHSDDDDVKQSKDQVYDSDDSDSEM------------------ 176
            |...:..||.:.| :||:.|.|....:.....:......|..:|:||
Mouse    12 PPESAPSKPSAAG-AGGSSSGNKGGPEGGAAPAAPCAAGSGPADTEMEEVFDHGSPGKQKEIQEP 75

  Fly   177 ----STKMTGQRKKVFQFMNEASLIELQSVKTLSEKKALAIIDVRPFSD--WSDLRQKLESIRMS 235
                ..||...|...|:::.:.:.:....::..::|...:.:.::|...  ..|.:|.|.|:
Mouse    76 DPTYEEKMQTDRANRFEYLLKQTELFAHFIQPAAQKTPTSPLKMKPGRPRVKKDEKQNLLSV--- 137

  Fly   236 GDLLNYA------QELINKQNTVAAILSKCNNMVSRLEKAISNGAGIVEQPKLLSSGLQLADYQI 294
            ||..:..      :||:.:.       ||..|:.:|.|          :.|..:..| :|.|||:
Mouse   138 GDYRHRRTEQEEDEELLTES-------SKATNVCTRFE----------DSPSYVKWG-KLRDYQV 184

  Fly   295 IGLNWLTVMHKQEMNGILADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVPSSTLDNWEAEISR 359
            .|||||..:::..:|||||||||||||:|.|:.|.|:|........|:::||.|||.||.:|..:
Mouse   185 RGLNWLISLYENGINGILADEMGLGKTLQTISLLGYMKHYRNIPGPHMVLVPKSTLHNWMSEFKK 249

  Fly   360 WCPELVVEKYHGSQDERRRMRGRFAKDGFT--GFDVLLTTYHIVGSTPEERKMFRVCKLDYVIFD 422
            |.|.|......|.:::    |..|.:|...  .:||.:|:|.::   .:|:.:|:.....|::.|
Mouse   250 WVPTLRSVCLIGDKEQ----RAAFVRDVLLPGEWDVCVTSYEML---IKEKSVFKKFNWRYLVID 307

  Fly   423 EAHMLKNMTTQRYANLITINARMRILLTGTPLQNNLLELISLLCFVMPKFFAKSIEDIKSLFAKK 487
            |||.:||..::....:.......|:|||||||||||.||.|||.|::|..| .|.:|..|.| ..
Mouse   308 EAHRIKNEKSKLSEIVREFKTTNRLLLTGTPLQNNLHELWSLLNFLLPDVF-NSADDFDSWF-DT 370

  Fly   488 GKSDGDQDEVSQFQETQIQRAKRIMKPFVLRRLKKDVLKNLPKKLSLVEKVPMSSQQKIYYHEL- 551
            ....|||        ..::|...:::||:|||:|.||.|:||.|..:...|.:|..|:.:|..:
Mouse   371 NNCLGDQ--------KLVERLHMVLRPFLLRRIKADVEKSLPPKKEVKIYVGLSKMQREWYTRIL 427

  Fly   552 ---VDYYSNNKGEVCSSSERAGIAIMMEMRRIANHPLLM------RHYFTDANLRGFSKRLANAS 607
               :|.. |:.|::   .:...:.|:|::|:..|||.|.      ..|.||.
Mouse   428 MKDIDIL-NSAGKM---DKMRLLNILMQLRKCCNHPYLFDGAEPGPPYTTDM------------- 475

  Fly   608 SFKKTNEQYIFEELAVMSDFQVYQMMNKHEFYDVKIPDNLICDSGKFLYLDTLLPKLKAEGHRVL 672
                                                  :|:.:|||.:.||.||||||.:|.|||
Mouse   476 --------------------------------------HLVTNSGKMVVLDKLLPKLKEQGSRVL 502

  Fly   673 LFSQFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDFNGDDSI-FVFLLSTKAGGVGINL 736
            :|||.|.:|||:|:|...|.:.:|||||.|..:.|||.|..:|..:|. |||:|||:|||:||||
Mouse   503 IFSQMTRVLDILEDYCMWRNYEYCRLDGQTPHDERQDSINAYNEPNSTKFVFMLSTRAGGLGINL 567

  Fly   737 TAADTCVIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIEEGILMAAEEKLKLEKDITS 801
            ..||..:::|.|:||..|.||.||.||:||.:.|.::|.|:::|:||.|:..||.||:|:..:.
Mouse   568 ATADVVILYDSDWNPQVDLQAMDRAHRIGQTKTVRVFRFITDNTVEERIVERAEMKLRLDSIVI- 631

  Fly   802 NEKGEVHEQ 810
             ::|.:.:|
Mouse   632 -QQGRLVDQ 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	6/42 (14%)
		HepA	<276..795	CDD:440319	192/531 (36%)
Smarca5	NP_444354.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..81		12/69 (17%)
		PLN03142	68..1011	CDD:215601	214/667 (32%)
		DEAH box	307..310		2/2 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1014..1051