Protein Alignment Etl1 and RAD5

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_197667.1
• Gene: RAD5 / 832338
• AraportID: AT5G22750
• Length: 1029
• Species: Arabidopsis thaliana
• Alignment Length: 783
• Identity: 191/783 - (24%)
• Similarity: 292/783 - (37%)
• Gaps: 276/783 - (35%)

  Fly   256 LSKCNNM-----VSRLEKAISNG-----AGIVEQPKLLSSGL-----------QLADYQIIGLNW 299
            |:|..||     ....|:.||:|     .|:.:     ||||           :|..||...|:|
plant   299 LNKVKNMNQDANGDENEQCISDGDLDNIVGVGD-----SSGLKEMETPHTLLCELRPYQKQALHW 358

  Fly   300 L-------------TVMH----------KQEM-----------------------NGILADEMGL 318
            :             |::|          |:|:                       .|||||.|||
plant   359 MTQLEKGNCTDEAATMLHPCWEAYCLADKRELVVYLNSFTGDATIHFPSTLQMARGGILADAMGL 423

  Fly   319 GKTIQVIA-----------------------------------------FLAYLK-----ENGLS 337
            |||:..|:                                         ||.:.|     ::.|.
plant   424 GKTVMTISLLLAHSWKAASTGFLCPNYEGDKVISSSVDDLTSPPVKATKFLGFDKRLLEQKSVLQ 488

  Fly   338 QAAHLIVVPSSTLDNWEAEISRWCP--ELVVEKYHGSQDERRRMRGRFAKDGFTGFDVLLTTYHI 400
            ...:|||.|.:.|..|:.||.....  .|.|..::|      :.|.:.|| ..:..||::|||.:
plant   489 NGGNLIVCPMTLLGQWKTEIEMHAKPGSLSVYVHYG------QSRPKDAK-LLSQSDVVITTYGV 546

  Fly   401 VGSTPEER-----------KMFRVCKLDYVIFDEAHMLKNMTTQRYANLITINARMRILLTGTPL 454
            :.|...:.           :.||      ::.||||.:||..:|.......:.|..|..|||||:
plant   547 LTSEFSQENSADHEGIYAVRWFR------IVLDEAHTIKNSKSQISLAAAALVADRRWCLTGTPI 605

  Fly   455 QNNLLELISLLCF--VMP--------KFFAKSIEDIKSLFAKKGKSDGDQDEVSQFQETQIQRAK 509
            ||||.:|.|||.|  :.|        |...|..|            :||        |..::..:
plant   606 QNNLEDLYSLLRFLRIEPWGTWAWWNKLVQKPFE------------EGD--------ERGLKLVQ 650

  Fly   510 RIMKPFVLRRLKKDVLKN------LPKKLSLVEKVPMSSQQKIYYHELVDYYSNNKGEVCSSSER 568
            .|:||.:|||.|....:.      ||...:.|....:|..::.:|..|   :..:|.:.....|:
plant   651 SILKPIMLRRTKSSTDREGRPILVLPPADARVIYCELSESERDFYDAL---FKRSKVKFDQFVEQ 712

  Fly   569 AGI--------AIMMEMRRIANHPLLMRHYFTDA---NLRGFSKRLANASSFKKTNE-------- 614
            ..:        .:::.:|:..:||.|:......|   :|...|||..:..|.....|
plant   713 GKVLHNYASILELLLRLRQCCDHPFLVMSRGDTAEYSDLNKLSKRFLSGKSSGLEREGKDVPSEA 777

  Fly   615 --QYIFEEL-----------------AVMSDFQ----------------------VYQMMNKHEF 638
              |.:.|||                 ||::...                      ....::|.|.
plant   778 FVQEVVEELRKGEQGECPICLEALEDAVLTPCAHRLCRECLLASWRNSTSGLCPVCRNTVSKQEL 842

  Fly   639 --------YDVKIPDNLICDSGKFLYLDTLLPKLKAEGHRVLLFSQFTMMLDIVEEYLRIRKFGF 695
                    :.|.:..|.: :|.|...|...|..|::.|.:.:||||:|..||:::..|....|.|
plant   843 ITAPTESRFQVDVEKNWV-ESSKITALLEELEGLRSSGSKSILFSQWTAFLDLLQIPLSRNNFSF 906

  Fly   696 CRLDGATAVNVRQDLITDFNGDDSIFVFLLSTKAGGVGINLTAADTCVIHDIDFNPYNDKQAEDR 760
            .||||..:...|:.::.:|:.|.||.|.|:|.||||||||||||....:.|..:||..::||..|
plant   907 VRLDGTLSQQQREKVLKEFSEDGSILVLLMSLKAGGVGINLTAASNAFVMDPWWNPAVEEQAVMR 971

  Fly   761 CHRMGQQRPVTIYRLISESTIEEGILMAAEEKLKLEKDITSNEKGEVHEQRCVVKLLTTALGLDK 825
            .||:||.:.|.|.|.|.:.|:||.:                 |..:..:||.:...||
plant   972 IHRIGQTKEVKIRRFIVKGTVEERM-----------------EAVQARKQRMISGALT------- 1012

  Fly   826 DQE 828
            |||
plant  1013 DQE 1015

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164
		HepA	<276..795	CDD:440319	174/718 (24%)
RAD5	NP_197667.1	UBA_like_SF	9..48	CDD:473871
		HIRAN	116..224	CDD:400928
		HepA	<339..1011	CDD:440319	173/725 (24%)
		RING_Ubox	789..842	CDD:473075	3/52 (6%)