Protein Alignment Etl1 and smarca2

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_031746549.1
• Gene: smarca2 / 734002
• XenbaseID: XB-GENE-1013843
• Length: 1606
• Species: Xenopus tropicalis
• Alignment Length: 882
• Identity: 265/882 - (30%)
• Similarity: 411/882 - (46%)
• Gaps: 187/882 - (21%)

  Fly    29 RINKNASSVVASPSR-----TERVPGKKRIQVMADSDSDGNDSQTPKKTKLELTVKEKEERYMAA 88
            :::|..::..|:..|     |||:..::..::||:.:.........||.:....:.::.:.|:|
 Frog   492 KLSKAVATWHANTEREQKKETERIEKERMRRLMAEDEEGYRKLIDQKKDRRLAYLLQQTDEYVA- 555

  Fly    89 AKISPHFDTMAIQESLSRTNWDVAASVRYLRENCKPKGHNGPLAKSKLKPRSNGISGGNFSDND- 152
                          :|:...|: ....:..:|..|.|      .|.|.:..:.|:..|...|.:
 Frog   556 --------------NLTSLVWE-HKKAQAAKEKKKKK------KKKKAEENAEGVGSGLGMDGEL 599

  Fly   153 ---------------HSDDDDV-------KQSKDQVY-------------DSDDSDSEMSTKMTG 182
                           |::...|       |.|:.:.:             ||:.|.||...:
 Frog   600 IDESSQMSDLPVKVIHTETGKVLLAPEAPKASQLETWLEMNPGYEVAPRSDSEGSSSEYEEE--- 661

  Fly   183 QRKKVFQFMNEASLIELQSVKTLSEKKALAI---IDVRPFSDWSDLRQKLESIRMSGDLLNYAQE 244
                  :...|:|.::.:      |||.|.:   .:|:     .|.:|.:|:.:...|.....||
 Frog   662 ------EDEEESSRLDTE------EKKRLGLNTEDNVK-----HDAKQIIETAKQDVDDEYSMQE 709

  Fly   245 LINKQNTVAAILSKCNNMVSRLEKAISNGAGIVEQPKLLSSGLQLADYQIIGLNWLTVMHKQEMN 309
            ...:..:...:   .:.:..|:||          |..||.:| .|..|||.||.|:..:....:|
 Frog   710 DARQSQSYYGV---AHAVTERVEK----------QSSLLING-SLKHYQIQGLEWMVSLFNNNLN 760

  Fly   310 GILADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVPSSTLDNWEAEISRWCPELVVEKYHGSQD 374
            ||||||||||||||.||.:.||.|:......:||:||.|||.||..|..:|.|.:|...|.|:..
 Frog   761 GILADEMGLGKTIQTIALITYLMEHKRLNGPYLIIVPLSTLSNWLYEFDKWAPSVVKIAYKGTPA 825

  Fly   375 ERRRMRGRFAKDGFTG-FDVLLTTYHIVGSTPEERKMFRVCKLDYVIFDEAHMLKN---MTTQRY 435
            .||.:..:..    || |:||||||..:   .:::.:....:..|:|.||.|.:||   ..||
 Frog   826 MRRSLVPQLR----TGKFNVLLTTYEYI---IKDKHILAKIRWKYMIVDEGHRMKNHHCKLTQ-- 881

  Fly   436 ANLITIN----ARMRILLTGTPLQNNLLELISLLCFVMPKFFAKSIEDIKSLFAKKGKSDGDQDE 496
                .:|    |..|||||||||||.|.||.:||.|::|..| ||....:..|.......|::.:
 Frog   882 ----VLNTHYVAPRRILLTGTPLQNKLPELWALLNFLLPTIF-KSCSTFEQWFNAPFAMTGERVD 941

  Fly   497 VSQFQET--QIQRAKRIMKPFVLRRLKKDVLKNLPKKLSLVEKVPMSSQQKIYYHELVDYYSNNK 559
            ::: :||  .|:|..::::||:||||||:|...||:|:..|.|..||:.|||.|..:     ..|
 Frog   942 LNE-EETILIIRRLHKVLRPFLLRRLKKEVESQLPEKVEYVIKCDMSALQKILYRHM-----QAK 1000

  Fly   560 GEVC---SSSERAG-------IAIMMEMRRIANHPLLMRHYFTD-ANLRGFSKRLANASSFKKTN 613
            |.:.   |..::.|       :..:|::|:|.|||.:.:|.... |...|:|..:.|.....:|
 Frog  1001 GILLTDGSEKDKKGKGGAKTLMNTIMQLRKICNHPFIFQHIEESFAEHLGYSNGIINGPDLYRT- 1064

  Fly   614 EQYIFEELAVMSDFQVYQMMNKHEFYDVKIPDNLICDSGKFLYLDTLLPKLKAEGHRVLLFSQFT 678
                                                 ||||..||.:||||:|..||||||.|.|
 Frog  1065 -------------------------------------SGKFELLDRILPKLRATNHRVLLFCQMT 1092

  Fly   679 MMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDFNGDDS-IFVFLLSTKAGGVGINLTAADTC 742
            .::.|:|:|...|.|.:.||||.|....|..|:..||.:.| .|:|||||:|||:|:||.||||.
 Frog  1093 SLMTIMEDYFAFRNFLYLRLDGTTKSEDRASLLKRFNEEGSPFFIFLLSTRAGGLGLNLQAADTV 1157

  Fly   743 VIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIEEGILMAAEEKLKLEKDITS----NE 803
            ||.|.|:||:.|.||:||.||:|||..|.:.||.:.:::||.||.||:.||.:::.:..    ::
 Frog  1158 VIFDSDWNPHQDLQAQDRAHRIGQQNEVRVLRLCTVNSVEEKILAAAKYKLNVDQKVIQAGMFDQ 1222

  Fly   804 KGEVHEQRCVVKLLTTALGLDKDQEEQLNNSLNNSIA 840
            |...||:|.   .|...|..::..|.|..:.|:..|:
 Frog  1223 KSSSHERRA---FLQAILEHEEQNESQKKDDLSGDIS 1256

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	10/43 (23%)
		HepA	<276..795	CDD:440319	208/540 (39%)
smarca2	XP_031746549.1	Atrophin-1	31..>467	CDD:460830
		QLQ	175..209	CDD:462622
		HSA	453..525	CDD:214727	6/32 (19%)
		BRK	605..648	CDD:462196	4/42 (10%)
		PLN03142	697..>1218	CDD:215601	214/592 (36%)
		DEXHc_SMARCA2	717..967	CDD:350821	103/278 (37%)
		SnAC	1293..1360	CDD:464219
		Bromo_SNF2L2	1416..1522	CDD:99947