Protein Alignment Etl1 and smarcal1

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_073768103.1
• Gene: smarcal1 / 560412
• ZFINID: ZDB-GENE-041210-303
• Length: 810
• Species: Danio rerio
• Alignment Length: 902
• Identity: 204/902 - (22%)
• Similarity: 324/902 - (35%)
• Gaps: 266/902 - (29%)

  Fly     5 TVAASASASASSSAKSSLSDLRQFRINKNASSVVASPSRTE---RVPGKKRIQVMADSDSDGNDS 66
            |.|::||:....:.|.|..:.|             .|...|   .:|.||
Zfish    93 TAASTASSFYGQAGKPSTGEKR-------------PPKPLEPAAHIPAKK--------------- 129

  Fly    67 QTPKKTKLELTVKEKEERYMAAAKISPHFDTMAIQESLSRTNWDVAASV--------RYLRENCK 123
              |..:.....|...|.|:  ..::..|.|.:.:.:|:...|:|.|..:        :.|.|..
Zfish   130 --PAVSLRGRCVSHSENRF--RVEVGYHADLILVFKSIPSKNYDPATKMWNFSLEDYQMLMEQV- 189

  Fly   124 PKGHNGPLAKSKLKPRSNGISGGNFSDNDHSDDDD--------------------------VKQS 162
              .|   |....||| ..|:.|.|.|.:.....|.                          |.:|
Zfish   190 --AH---LPSISLKP-LEGMEGLNISASTCRPKDAAAMPALMRLCQGWQKPGATIKGKCVLVSRS 248

  Fly   163 KDQV---YDSD--DSDSEMSTKMTGQRKKVFQFMNE------ASLIELQSVKTLSEKKALAIIDV 216
            :.:|   |.:|  ....:|.:|....:.:.:.|:.|      |.|.||.:|:|  |....|::
Zfish   249 RLEVDIGYQADVIGIFKQMPSKSYDMKTRKWTFLLEDYGKLMADLNELPTVET--EPLPHAVL-- 309

  Fly   217 RPFSDWSDLRQKLESIRMSGDLLNYAQELINKQNTVAAILSKCNNMVSRLEKAISNGAGIVEQPK 281
            :.||...:..:....:....||                         |.::            |:
Zfish   310 QSFSSQFEKTESRAPVPPEADL-------------------------SHID------------PQ 337

  Fly   282 LLSSGLQLADYQIIGLNWLTVMHKQEMNGILADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVP 346
            |..|   |..:|..|:|:..   .:|...:|||:||||||:|.|...||.:    |:...|:|.|
Zfish   338 LTRS---LMPFQRDGVNFAV---SREGRLLLADDMGLGKTVQAICIAAYYR----SEWPLLVVAP 392

  Fly   347 SSTLDNWEAEISRWCPEL------VVEKYHGSQDERRRMRGRFAKDGFTGFDVLLTTYHIVGSTP 405
            ||....|.....||.|.:      ||.|               .||......:.:.:|.::....
Zfish   393 SSVRFTWAEAFRRWLPSVKPDSINVVVK---------------GKDNLRSGLINIISYDLLNKMD 442

  Fly   406 EE--RKMFRVCKLDYVIFDEAHMLKNMTTQRYANLITI--NARMRILLTGTPLQNNLLELISLLC 466
            ::  ...|.|     :|.||:|.||||.|.|....:.:  .|:..|||:|||..:...||.:.:.
Zfish   443 KQPPSSPFNV-----IIMDESHFLKNMKTARCRAALPLLKTAKRVILLSGTPAMSRPAELYTQIQ 502

  Fly   467 FVMPKFFAKSIEDIKSLF--AKKGKSDGDQDEVSQFQETQIQRAKRIMKPFVLRRLKKDVLKNLP 529
            .|.|..|.: ..|..:.:  ||:.....|....|...|.::...:.:|    |||||.:||..||
Zfish   503 AVRPALFPR-FHDFGTRYCDAKQLPWGWDYSSSSNLTELKLLLEESLM----LRRLKSEVLSQLP 562

  Fly   530 KKLSLVEKVP---MSSQQKIYYH----ELVDYYSNNKGEVCSSSERAGIAIMMEMRRIANHPLLM 587
            .|...|..|.   ::|:.|...:    ||...|.|      .|.|:..:.:..      ||.
Zfish   563 AKQRKVVTVTTDGINSRTKAALNAAARELAKGYHN------KSQEKEALLVFF------NHT--- 612

  Fly   588 RHYFTDANLRGFSKRLANASSFKKTNEQYIFEELAVMSDFQVYQMMNKHEFYDVKIPDNLICDSG 652
                .:|.:|                        |:|            |:    |.|.|.|...
Zfish   613 ----AEAKIR------------------------AIM------------EY----ISDMLECGRE 633

  Fly   653 KFLYLDTLLPKLKAEGHRVLLFSQFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDFNGD 717
            ||                 |:|:...::||.:.:.|..:...|.|:||:|....||.|...|...
Zfish   634 KF-----------------LVFAHHKLVLDSITKELGEKSISFIRIDGSTPSAERQLLCERFQAS 681

  Fly   718 DSIFVFLLSTKAGGVGINLTAADTCVIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIE 782
            ....|.:||..|..:|:.|.:|...|..::.:||....|||||.||:||...|.|:.|:::.|.:
Zfish   682 QQSCVAVLSITAANMGLTLHSAALVVFAELFWNPGVLIQAEDRVHRIGQTSNVDIHYLVAKGTAD 746

  Fly   783 EGILMAAEEKLKL-------EKDITSN-EKGEVHEQRCVVKLLTTALGLDKDQEEQL 831
            :.:....:.|:.:       |.:|:.| |....|.:......:|.......|::|.|
Zfish   747 DYLWPMIQAKMNVLEQVGLSESNISENAESASFHSRDRQQLTITEMFQRSFDEDEML 803

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	11/46 (24%)
		HepA	<276..795	CDD:440319	139/537 (26%)
smarcal1	XP_073768103.1	None