Protein Alignment Etl1 and dom

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: NP_001286676.1
• Gene: dom / 45655
• FlyBaseID: FBgn0020306
• Length: 3233
• Species: Drosophila melanogaster
• Alignment Length: 1283
• Identity: 302/1283 - (23%)
• Similarity: 445/1283 - (34%)
• Gaps: 534/1283 - (41%)

  Fly     7 AASASASASSSAKSSLSDLRQF-------------RINKNASSVVASPSRTERVPGKKRIQVMAD 58
            ||......::.||.|..|...|             ::.|...|   |..:||........:..|.
  Fly   715 AADVKEEVTALAKESEMDFDDFLNDLPPGYLENRDKLMKEEQS---SAIKTETPDDSDDSEFEAK 776

  Fly    59 SDSDGNDSQTPKKTKLELTVKEKEERYMAAAKISPHFDTMAIQESLSRTNWDVAASVRYLRENCK 123
            ..||.:::...|:.:.|..:..|:|           .|.:.....|         ||..|....|
  Fly   777 EASDDDENTISKQEEAEQEIDHKKE-----------IDELEADNDL---------SVEQLLAKYK 821

  Fly   124 PKGHNGPLAKSKLKPRSNGISGGNFSDNDHSDDDDVKQSKDQVYDSDDSDSEMSTKMTGQRKKVF 188
            .:....| .:.||.||...:.    ||:|.:..|..::|:|...:.::..|.:.|...
  Fly   822 SEQPPSP-KRRKLAPRDPELD----SDDDSTAVDSTEESEDAATEDEEDLSTVKTDTD------- 874

  Fly   189 QFMNEASLIELQSVKTLSEKKALAIIDVRPFSDWSDLRQKLESIRMSG---DLLN----YAQELI 246
                    :|.|..:....|..:|..|....:..|.     .:...||   |:||    .|:.|.
  Fly   875 --------MEEQDEQEDGLKSLMADADATSGAAGSG-----STAGASGNKDDMLNDAAALAESLQ 926

  Fly   247 NKQNTVAAILSKCNNMVSRLEKAISNGAGIVEQPKLLSSGLQLADYQIIGLNWLTVMHKQEMNGI 311
            .|.||:::     .|:|:.:             |.||...|:  :||.|||:||..|:::::|||
  Fly   927 PKGNTLSS-----TNVVTPV-------------PFLLKHSLR--EYQHIGLDWLVTMNERKLNGI 971

  Fly   312 LADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVPSSTLDNWEAEISRWCPELVVEKYHGSQDER 376
            ||||||||||||.||.||:|.....:...||||||||.:.|||.|..:|||...:..|:|||.||
  Fly   972 LADEMGLGKTIQTIALLAHLACAKGNWGPHLIVVPSSVMLNWEMEFKKWCPGFKILTYYGSQKER 1036

  Fly   377 RRMRGRFAKDGFTGFDVLLTTYHIVGSTPEERKMFRVCKLDYVIFDEAHMLKNMTTQRYANLITI 441
            :..|..:.|.  ..|.|.:|:|.:|   .::::.||..|..|:|.|||..:||..:||:..|:..
  Fly  1037 KLKRVGWTKP--NAFHVCITSYKLV---VQDQQSFRRKKWKYLILDEAQNIKNFKSQRWQLLLNF 1096

  Fly   442 NARMRILLTGTPLQNNLLELISLLCFVMPKFFAKSIEDIKSLFAK--KGKSDGDQDEVSQFQETQ 504
            :...|:|||||||||:|:||.||:.|:||..|: |..:.|..|:.  .|..:|:.    ::.||.
  Fly  1097 STERRLLLTGTPLQNDLMELWSLMHFLMPYVFS-SHREFKEWFSNPMTGMIEGNM----EYNETL 1156

  Fly   505 IQRAKRIMKPFVLRRLKKDVLKNLPKKLSLVEKVPMSSQQKIYYHELVDYYSNNK-------GEV 562
            |.|..::::||:||||||:|.|.:|||...|....:|::|:..|.   |:.|..|       |.:
  Fly  1157 ITRLHKVIRPFLLRRLKKEVEKQMPKKYEHVITCRLSNRQRYLYE---DFMSRAKTRETLQTGNL 1218

  Fly   563 CSSSERAGIAIMMEMRRIANHP------------------------------------------- 584
            .|.     |.::|::|::.|||
  Fly  1219 LSV-----INVLMQLRKVCNHPNMFEARPTISPFQMDGITFHTPRLVCDIMEYDPFTQINLETLN 1278

  Fly   585 LLMRH------------------------------------------------------------ 589
            ||:.|
  Fly  1279 LLLLHLEQTMTAYVSHKSRLLAPPRKLIEDIDTAPLPAPRCPNGKYRFHIRVRSAELAQRIKLNA 1343

  Fly   590 ----------------------------------------------------------------- 589
                                                                             
  Fly  1344 VKVGASPAMRLEGSKIMPMRNLLPSGRVLKRVSASINPVNMALKPVVINSVVTTTSSSTTASSPT 1408

  Fly   590 -------------------------------------YFTDANLRG--------FSKRLANAS-- 607
                                                 |.|.|...|        .||..|:||
  Fly  1409 GALSVLSNSKLLGARSQINAPTPAKVAKTMQDGKPFFYLTPATNSGAAGARLTLTSKTTASASTT 1473

  Fly   608 ----------------------------------------------------------------- 607
                                                                             
  Fly  1474 TSRTTVTASTTSGQQLIRDPIVKDLATHVKSTVQKQSIANGKTEPEEETEAEDPYKVQELIQMRK 1538

  Fly   608 ----------------------------------------SFKKTNEQ---YI------------ 617
                                                    |.|::..|   |.
  Fly  1539 EQRLAALKRMAMINRRRTDATPIYGEDCREAIQRCMQATRSLKRSTWQTRGYANCCTAMAHRNGW 1603

  Fly   618 --------FEELA-----VMSDFQVY--------------QMMNKHEFYD--------------- 640
                    |||..     |.::|.:|              .:.:.|..::
  Fly  1604 SLNHLLKSFEERCADLKPVFANFVIYVPSVCAPRIRRYVQNLSSTHWQHEQRIENIVDQALRPKL 1668

  Fly   641 -----------VKIPDNLIC--DSGKFLYLDTLLPKLKAEGHRVLLFSQFTMMLDIVEEYLRIRK 692
                       .|.||..:.  |.||...:|.||.:||..|||||:|:|.|.|||::|.:|....
  Fly  1669 ALLHPIISEMTTKFPDPRLIQYDCGKLQTMDRLLRQLKVNGHRVLIFTQMTKMLDVLEAFLNYHG 1733

  Fly   693 FGFCRLDGATAVNVRQDLITDFNGDDSIFVFLLSTKAGGVGINLTAADTCVIHDIDFNPYNDKQA 757
            ..:.||||:|.|..||.|:..||||..||.|:|||::||||||||.|||.:.:|.|:||..|.||
  Fly  1734 HIYLRLDGSTRVEQRQILMERFNGDKRIFCFILSTRSGGVGINLTGADTVIFYDSDWNPTMDAQA 1798

  Fly   758 EDRCHRMGQQRPVTIYRLISESTIEEGILMAAEEKLKL--------------------------- 795
            :|||||:||.|.|.||||:||.|||..||..|.:|..|
  Fly  1799 QDRCHRIGQTRDVHIYRLVSERTIEVNILKKANQKRMLSDMAIEGGNFTTTYFKSSTIKDLFTME 1863

  Fly   796 --EKDITSNEKGEVHEQRCVVKLLTTALGLDKDQEEQLNNSLNNSIAS 841
              |:|.:|.||.|..::......|:.......:.|:|...:..:::|:
  Fly  1864 QSEQDESSQEKSENKDRIVATTTLSDTPSTVVETEKQSLRAFEHALAA 1911

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	6/40 (15%)
		HepA	<276..795	CDD:440319	235/917 (26%)
dom	NP_001286676.1	HSA	543..614	CDD:214727
		HepA	692..>1235	CDD:440319	183/605 (30%)
		DEXQc_SRCAP	949..1171	CDD:350761	101/233 (43%)
		SF2_C_SNF	1685..1817	CDD:350180	70/131 (53%)
		DISARM_DrmD_b	<1702..>1936	CDD:468472	86/210 (41%)
		HEC1	<1858..>2031	CDD:444066	10/54 (19%)
		SP1-4_N	2486..>2819	CDD:425404