Protein Alignment Etl1 and Chd6

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_008760567.1
• Gene: Chd6 / 311607
• RGDID: 1310465
• Length: 2711
• Species: Rattus norvegicus
• Alignment Length: 880
• Identity: 266/880 - (30%)
• Similarity: 394/880 - (44%)
• Gaps: 197/880 - (22%)

  Fly    11 SASASSSAKSSLSDLRQFRINKNAS-SVVASPSRTERVPGKKRIQVMADS-------DSDGNDSQ 67
            |.||.|..:.|...:::.:.|::.. .||.....|..|.|..|...::.|       :...:|:.
  Rat   227 SESADSQKRRSGRQVKRRKYNEDLDFKVVDDDGETIAVLGAGRTSALSASTLAWQAEEPPEDDAN 291

  Fly    68 TPKKTKLELTVKEKEERYMAAAKISPHFDTMAI-----QESLSRTNWDVAASVRYLRENCKPKGH 127
            ..:|.....||:|....       .|.||....     ..|.....|   |::..|.::
  Rat   292 IIEKILASKTVQEVHPG-------EPPFDLELFYVKYRNFSYLHCKW---ATMEELEKD------ 340

  Fly   128 NGPLAKSKLKPRSNGISGGNF----SDNDHSDDDDVKQSKDQVYD-SDDSDSEMSTKMTGQRKK- 186
              |....|:|...|..:....    .|.|..:.|.::  .|::.: :...|:|...::|....|
  Rat   341 --PRIAQKIKRFRNKQAQMKHIFTEPDEDLFNPDYIE--IDRILEVAHTKDAETGEEVTHYLVKW 401

  Fly   187 -----------VFQFMNEASLIELQSVKTLSEKKALAIIDVRPFSD-WSDLRQKLESIRMSGDLL 239
                       :.:.::.|.:.|.:|::.|.|.|.:.    ||.|| |    ||||:.|
  Rat   402 CSLPYEESTWELEEDVDPAKVKEFESLQILPEVKPVE----RPASDAW----QKLETSR------ 452

  Fly   240 NYAQELINKQNTVAAILSKCNNMVSRLEKAISNGAGIVEQPKLLSSGLQLADYQIIGLNWLTVMH 304
                                       |...||               :|.:||:.|:|||....
  Rat   453 ---------------------------EYKNSN---------------RLREYQLEGMNWLLFNW 475

  Fly   305 KQEMNGILADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVPSSTLDNWEAEISRWCPELVVEKY 369
            ....|.|||||||||||||.||||:.:...|: ....||:.|.||:.|||.|...| .|:....|
  Rat   476 YNRKNCILADEMGLGKTIQSIAFLSEIFVRGI-HGPFLIIAPLSTITNWEREFRTW-TEMNAIVY 538

  Fly   370 HGSQDERR-----RMRGRFAK----DGFTGFDVLLTTYH-IVGSTPEERKMFRVCKLDYVIFDEA 424
            ||||..|:     .|..|.|:    .|...|.|::||:. |:...||.:|:...|    |:.|||
  Rat   539 HGSQISRQMIQQYEMVYRDAQGNPLSGVFKFHVVITTFEMILADCPELKKIHWSC----VVIDEA 599

  Fly   425 HMLKNMTTQRYANLITINARMRILLTGTPLQNNLLELISLLCFVMPK------FFAKSIEDIKSL 483
            |.|||...:....|..:....::|||||||||::.||.|||.|:.|.      .|.:...|:|:
  Rat   600 HRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELFSLLNFLEPSQFPSETAFLEEFGDLKT- 663

  Fly   484 FAKKGKSDGDQDEVSQFQETQIQRAKRIMKPFVLRRLKKDVLKNLPKKLSLVEKVPMSSQQKIYY 548
                              |.|:::.:.|:||.:|||||.||.|||..|...:.:|.:::.||.||
  Rat   664 ------------------EEQVKKLQSILKPMMLRRLKDDVEKNLAPKQETIIEVELTNIQKKYY 710

  Fly   549 HELVDYYSNNKGEVCSSSERAG----IAIMMEMRRIANHPLLMRHYFTDANLRGFSKRLANASSF 609
            ..:::   .|...:...:.:..    |..|||:|:..|||.|         :.|..:::  ...|
  Rat   711 RAILE---KNFSFLTKGANQHNMPNLINTMMELRKCCNHPYL---------INGAEEKI--LEDF 761

  Fly   610 KKTNEQYIFEELAVMSDFQVYQMMNKHEFYDVKIPDNLICDSGKFLYLDTLLPKLKAEGHRVLLF 674
            :|.:.       :..||||:..|:..               :||.:.:|.|||||.|.||:||:|
  Rat   762 RKAHS-------SEASDFQLQAMIQA---------------AGKLVLIDKLLPKLIAGGHKVLIF 804

  Fly   675 SQFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDF-NGDDSIFVFLLSTKAGGVGINLTA 738
            ||....|||:|:||..|::.:.|:||....|:||..|..| ..|...|||||.|:|||:||||||
  Rat   805 SQMVRCLDILEDYLIQRRYTYERIDGRVRGNLRQAAIDRFCKPDSDRFVFLLCTRAGGLGINLTA 869

  Fly   739 ADTCVIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIEEGILMAAEEKLKLEKDITS-- 801
            ||||:|.|.|:||.||.||:.||||:||.:.|.:||||:.::.|..:...|..||.|:|.|..
  Rat   870 ADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMFDKASLKLGLDKAILQDI 934

  Fly   802 NEKGEVHEQRCVVK------LLTTALGLDKDQEEQ 830
            |.||..:..:.:.|      |...|.|...|:|::
  Rat   935 NRKGSTNGVQQLSKMEVEDLLRKGAYGALMDEEDE 969

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	15/41 (37%)
		HepA	<276..795	CDD:440319	198/539 (37%)
Chd6	XP_008760567.1	PTZ00449	<100..372	CDD:185628	31/162 (19%)
		CD1_tandem_CHD5-9_like	287..352	CDD:349315	15/82 (18%)
		CD2_tandem_CHD5-9_like	371..429	CDD:349310	9/59 (15%)
		PLN03142	459..>984	CDD:215601	210/572 (37%)
		DEAD-like_helicase_N	460..681	CDD:475120	90/245 (37%)