Protein Alignment Etl1 and chd6

DIOPT Version :10

• Sequence 1: NP_609320.2
• Gene: Etl1 / 34311
• FlyBaseID: FBgn0032157
• Length: 844
• Species: Drosophila melanogaster
• Sequence 2: XP_004918574.2
• Gene: chd6 / 100498254
• XenbaseID: XB-GENE-5964535
• Length: 2667
• Species: Xenopus tropicalis
• Alignment Length: 962
• Identity: 276/962 - (28%)
• Similarity: 415/962 - (43%)
• Gaps: 243/962 - (25%)

  Fly    31 NKNASSVVASPSRTERVPGKKRIQVMADSDSDGNDSQTPKKTKLELTVKE-------KEERYMAA 88
            |...........|.::.||::::       :.....:.|||.|....|||       ||::...:
 Frog    86 NSGGGGTGVKKKRKKKEPGEEKV-------AKPKKKKEPKKVKEPKKVKEPSEAKDPKEQKQPKS 143

  Fly    89 AK----------ISPHFDTMAIQESLSRTNWDVAASVRYLRENCKPKGHNGPLAKSKLKPRSNGI 143
            .|          ..|.....|.|:|.::|               |||..:.....:.|:.:..|.
 Frog   144 PKEPKKPRKPREPKPPKQKKANQDSAAKT---------------KPKKLSKEQGPTPLEKKKKGK 193

  Fly   144 SGGNFS----DNDHSDDDDVKQSKDQVYDSDDSDSEMSTKMTGQRK-------KVFQFMNE---- 193
            ....||    |.:.|..:...||.::..:|.||....|.:...:||       ||.....|
 Frog   194 RKAEFSEESLDGEPSLLNPASQSTEESTESLDSQKRRSGRQVKRRKYNEDLDFKVVDDDGETIAV 258

  Fly   194 -------------------------ASLIELQSVKTLSEKKAL----------AIIDVRPFS--- 220
                                     |::||......:|:|:.:          ..:..|.||
 Frog   259 LGAGRASALSASTLAWQAEEPPEDDANIIERILSSRISQKEFMHAGIPLEVEEFYVKYRNFSYLH 323

  Fly   221 -DWSDL---------RQKLESIR------------MSGDLLN--YAQ-----ELINKQNT----- 251
             .|:.|         :||::..|            ...|:.|  |.:     |:.:.:::
 Frog   324 CKWATLEELEKDPRIQQKIKRFRNKQAQMKHIFTEPDEDMFNPDYVEVDRVLEVAHTKDSDTGEV 388

  Fly   252 --VAAILSK-CN----NMVSRLE-----------KAISNGAGI--VEQP------KLLSS----- 285
              |...|.| |:    .....||           :|:.....:  :|:|      ||:||
 Frog   389 REVTHFLVKWCSLPYEESTWELEEDVDPVKVKEFEALQKVPDLTPMERPASETWQKLVSSRTYKN 453

  Fly   286 GLQLADYQIIGLNWLTVMHKQEMNGILADEMGLGKTIQVIAFLAYLKENGLSQAAHLIVVPSSTL 350
            ..||.:||:.|:|||........|.|||||||||||||.|.||:.:...|: :...||:.|.||:
 Frog   454 NNQLREYQLEGMNWLLFNWYNRKNCILADEMGLGKTIQSITFLSEIFFMGI-RGPFLIIAPLSTI 517

  Fly   351 DNWEAEISRWCPELVVEKYHGSQDERRRMR--GRFAKD-------GFTGFDVLLTTYH-IVGSTP 405
            .|||.|...| .|:....|||||..|:.:.  ..:.:|       |...|.:::||:. |:...|
 Frog   518 TNWEREFRTW-TEMNTIVYHGSQISRQMIHQYEMYYRDEQGTPIPGIYKFQIVITTFEMILADCP 581

  Fly   406 EERKMFRVCKLDYVIFDEAHMLKNMTTQRYANLITINARMRILLTGTPLQNNLLELISLLCFVMP 470
            |.:|:...|    ||.||||.|||...:....|..:....::|||||||||::.||.|||.|:.|
 Frog   582 ELKKIRWSC----VIIDEAHRLKNRNCKLLEGLKLMALEHKVLLTGTPLQNSVEELYSLLNFLEP 642

  Fly   471 ------KFFAKSIEDIKSLFAKKGKSDGDQDEVSQFQETQIQRAKRIMKPFVLRRLKKDVLKNLP 529
                  ..|.:...|:|:                   |.|:::.:.|:||.:|||||.||.|||.
 Frog   643 VQFPSESTFLEEFGDLKT-------------------EEQVKKLQSILKPMMLRRLKDDVEKNLA 688

  Fly   530 KKLSLVEKVPMSSQQKIYYHELVD--YYSNNKGEVCSSSERAGIAIMMEMRRIANHPLLMRHYFT 592
            .|...:.:|.:::.||.||..:::  :....||....:.... |..|||:|:..|||.|
 Frog   689 PKQETIIEVELTNIQKKYYRAILEKNFTFLTKGANQHNMPNL-INTMMELRKCCNHPYL------ 746

  Fly   593 DANLRGFSKRLANASSFKKTNEQYIFEELAVMSDFQVYQMMNKHEFYDVKIPDNLICDSGKFLYL 657
               :.|..:::  ...|:|.:.....       |||:..|:..               :||.:.:
 Frog   747 ---INGAEEKI--LEDFRKRHSPDAL-------DFQLQAMIQA---------------AGKLVLI 784

  Fly   658 DTLLPKLKAEGHRVLLFSQFTMMLDIVEEYLRIRKFGFCRLDGATAVNVRQDLITDF-NGDDSIF 721
            |.|||||.|.||:||:|||....|||:|:||..|::.:.|:||....|:||..|..| ..|...|
 Frog   785 DKLLPKLIAGGHKVLIFSQMVRCLDILEDYLIQRRYIYERIDGRVRGNLRQAAIDRFCKPDSDRF 849

  Fly   722 VFLLSTKAGGVGINLTAADTCVIHDIDFNPYNDKQAEDRCHRMGQQRPVTIYRLISESTIEEGIL 786
            ||||.|:|||:||||||||||:|.|.|:||.||.||:.||||:||.:.|.:||||:.::.|..:.
 Frog   850 VFLLCTRAGGLGINLTAADTCIIFDSDWNPQNDLQAQARCHRIGQSKAVKVYRLITRNSYEREMF 914

  Fly   787 MAAEEKLKLEKDITS--NEKGEVHEQRCVVK------LLTTALGLDKDQEEQ 830
            ..|..||.|:|.:..  |.||..:..:.:.|      |...|.|...|:|::
 Frog   915 DKASLKLGLDKAVLQDINRKGNTNGVQPLSKIEVEDLLRKGAYGALMDEEDE 966

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Etl1	NP_609320.2	ComEA	<192..233	CDD:441164	13/92 (14%)
		HepA	<276..795	CDD:440319	202/550 (37%)
chd6	XP_004918574.2	CD1_tandem_CHD5-9_like	281..347	CDD:349315	12/65 (18%)
		CD2_tandem_CHD5-9_like	366..426	CDD:349310	9/59 (15%)
		PLN03142	456..>981	CDD:215601	207/570 (36%)
		DEXHc_CHD6	457..678	CDD:350816	87/245 (36%)