Protein Alignment CG13124 and CTIF

DIOPT Version :10

• Sequence 1: NP_609319.2
• Gene: CG13124 / 34310
• FlyBaseID: FBgn0032156
• Length: 510
• Species: Drosophila melanogaster
• Sequence 2: XP_005258449.1
• Gene: CTIF / 9811
• HGNCID: 23925
• Length: 616
• Species: Homo sapiens
• Alignment Length: 546
• Identity: 122/546 - (22%)
• Similarity: 187/546 - (34%)
• Gaps: 163/546 - (29%)

  Fly     1 MAEKVELL-AQASMNGQQNDTRKVRKSP---------EFQPGVISRERSFVRTSNQQNINKRRSL 55
            |..:||:. .:.....::||.|:.::.|         :.|||           |.:.|.:.::|
Human   190 MPHEVEIAHTKKLFRRRRNDRRRQQRPPGGNKPQQHGDHQPG-----------SAKHNRDHQKS- 242

  Fly    56 AFNVPGNQTGQMRGKPAMDIYRPPNVR---GELAAPAGGVGGDGPNGAIGGVANKLNVNAQEFTM 117
               ..|.......|:|....| ..|.|   |.:..|.|..|..|.:.           ||:| ||
Human   243 ---YQGGSAPHPSGRPTHHGY-SQNRRWHHGNMKHPPGDKGEAGAHR-----------NAKE-TM 291

  Fly   118 TTSSGAPAEALGNRSSLILPLTNGPGVGVAPGLGPYGNVNRRQAGHSLGNMPGLKANHRSILVTY 182
            |..:....:..|:                              .|||....|      ||.....
Human   292 TIENPKLEDTAGD------------------------------TGHSSLEAP------RSPDTLA 320

  Fly   183 PINTGALSGQLPLMNSPSSGNILHTTNRVKFAPEPRGHKVASHNQFGQLNNNYAQPYQANINGVD 247
            |:.:..|..|      .|.|..:.|..:....||..|.:
Human   321 PVASERLPPQ------QSGGPEVETKRKDSILPERIGER-------------------------- 353

  Fly   248 PYMNGNALQRSKSLSSADALTRGMAGLGLGLGNEVADIGQFTPE-------IQAL---------I 296
            |.:  ..||.||     |.|.|   .|...:.:||| :...||:       |:.|         :
Human   354 PKI--TLLQSSK-----DRLRR---RLKEKVPDEVA-VETTTPQQNKMDKLIEILNSMRNNSSDV 407

  Fly   297 DTAL-----EDPNKLNS-RCLMELTSQFIKRAVESRRFALPISRLCLNI-IAREQKETFLEALLN 354
            ||.|     |..|..|| ..|.|:.....::||..|.||...::||..: :...:...|...|||
Human   408 DTKLTTFMEEAQNSTNSEEMLGEIVRTIYQKAVSDRSFAFTAAKLCDKMALFMVEGTKFRSLLLN 472

  Fly   355 TCRQWYQEREKLLFAIQGMKSPSRVRFTAFMAFLTEMFCQLKRRQLQLRTHHEGTPPPL-VLLSL 418
            ..::.:..||:|       :.....|:..|:.||.|:|          .|....|..|. ||:..
Human   473 MLQKDFTVREEL-------QQQDVERWLGFITFLCEVF----------GTMRSSTGEPFRVLVCP 520

  Fly   419 LSKCCGDCVRPPIRSLSEIECLFYVLTCIGQDMEQQLPQQLELLMSLVRDAFLNAGESAASIRRT 483
            :..|..:.::........:.|....|...|:.:|:|||:.:..|::..||..|...||..: |..
Human   521 IYTCLRELLQSQDVKEDAVLCCSMELQSTGRLLEEQLPEMMTELLASARDKMLCPSESMLT-RSL 584

  Fly   484 LLQLIELKASHWQ-LPGNTVLYYTHT 508
            ||::|||.|:.|. |......||..|
Human   585 LLEVIELHANSWNPLTPPITQYYNRT 610

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13124	NP_609319.2	MIF4G	280..494	CDD:397130	62/237 (26%)
CTIF	XP_005258449.1	MIF4G	394..595	CDD:397130	57/218 (26%)