DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13124 and ctif

DIOPT Version :9

Sequence 1:	NP_001162923.1	Gene:	CG13124 / 34310	FlyBaseID:	FBgn0032156	Length:	510	Species:	Drosophila melanogaster
Sequence 2:	NP_001072334.1	Gene:	ctif / 779787	XenbaseID:	XB-GENE-5882041	Length:	583	Species:	Xenopus tropicalis

Alignment Length:	377	Identity:	78/377 - (20%)
Similarity:	138/377 - (36%)	Gaps:	63/377 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 GPYGNVNRRQAGHSLGNMPG-----------LKANHRSILVTY-PI----NTGALSGQLPLMNSP 199
            |.:|....|:..|:..::|.           ||....|:...: |:    ||.:.....|    |
Frog   245 GHHGYSQNRRWHHNQKHLPNDLQRNAKETDTLKIEDASVCTVHIPLDIHSNTDSTERHCP----P 305

  Fly   200 SSGNILHTTNRVKFAPEPRGHKVASHNQFGQLNNNYAQPYQANINGVDPYMNGNALQRSKSLSSA 264
            ::.:.......::....|:...:.|...  :|.....:.....:...:|       |::|.....
Frog   306 ANDSEAKRKESIQSRDRPKISLLQSSKD--RLRRRLKEKEDVAVESTNP-------QKTKMDKLI 361

  Fly   265 DALTRGMAGLGLGLGNEVADIGQFTPEIQALIDTALEDPNKLNS-RCLMELTSQFIKRAVESRRF 328
            :.|.        .:.|..:|:........|      |..|..|| ..|.|:.....::||..|.|
Frog   362 EILN--------SMRNNSSDVDYKLTTFMA------EAQNSANSEEMLGEIVKTIYQKAVTDRSF 412

  Fly   329 ALPISRLCLNI-IAREQKETFLEALLNTCRQWYQEREKLLFAIQGMKSPSRVRFTAFMAFLTEMF 392
            |...::||..: :...:...|...|||..::.:..||:       |......|:..|:.||.|:|
Frog   413 AHTAAKLCDRMALFMVEGTKFRSLLLNMLQKDFSIREE-------MHRSDVERWLGFITFLCEVF 470

  Fly   393 CQLKRRQLQLRTHHEGTPPPLVLLSLLSKCCGDCVRPPIRSLSEIECLFYVLTCIGQDMEQQLPQ 457
            ..::....:         |..||:..:..|..:.::........:.|....|...|:.:|.|||:
Frog   471 GTMRSNMAE---------PFRVLVCPIYTCLRELLQSEDVKEDAVLCCSMELQSAGRLLEDQLPE 526

  Fly   458 QLELLMSLVRDAFLNAGESAASIRRTLLQLIELKASHWQ-LPGNTVLYYTHT 508
            .:..|::..||..|...||..: |..||::|||.|:.|. |......||..|
Frog   527 MMSELLATARDKMLCPSESMLT-RSLLLEVIELHANSWNPLTPTITQYYNKT 577

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13124	NP_001162923.1	MIF4G	280..494	CDD:280935	53/215 (25%)
ctif	NP_001072334.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	42..95
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	129..154
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	190..251		2/5 (40%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	294..325		5/34 (15%)
		MIF4G	361..562	CDD:280935	54/231 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	72	1.000	Domainoid score	I9177
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR23254
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010