DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS2 and RPS2

DIOPT Version :9

Sequence 1:	NP_001260303.1	Gene:	RpS2 / 34309	FlyBaseID:	FBgn0004867	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_011392.1	Gene:	RPS2 / 852754	SGDID:	S000003091	Length:	254	Species:	Saccharomyces cerevisiae

Alignment Length:	245	Identity:	151/245 - (61%)
Similarity:	184/245 - (75%)	Gaps:	2/245 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 RGGRGGRGRGRGRWARGRGKEDSKEWVPVTKLGRLVREGKIKSLEEIYLYSLPIKEFEIIDFFLG 82
            |||.|||.|||.. .||....:.|.|||||||||||:.|||.::|||:|:|||:|||:|||..|
Yeast    11 RGGFGGRNRGRPN-RRGPRNTEEKGWVPVTKLGRLVKAGKITTIEEIFLHSLPVKEFQIIDTLL- 73

  Fly    83 SSLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDNNGHIGLGVKCSKEVATAIRGAIILAKLSVVP 147
            ..|:|||:.|.||||||||||||||||.|.:||:|||:|||:|.:||||.|||..||:|||||:|
Yeast    74 PGLQDEVMNIKPVQKQTRAGQRTRFKAVVVVGDSNGHVGLGIKTAKEVAGAIRAGIIIAKLSVIP 138

  Fly   148 VRRGYWGNKIGKPHTVPCKVTGKCGSVSVRLIPAPRGTGIVSAPVPKKLLTMAGIEDCYTSARGS 212
            :||||||..:|:||::..|.|||||||:|||||||||:|||::|..||||.:||:||.||.:.|.
Yeast   139 IRRGYWGTNLGQPHSLATKTTGKCGSVTVRLIPAPRGSGIVASPAVKKLLQLAGVEDVYTQSNGK 203

  Fly   213 TGTLGNFAKATYAAIAKTYAYLTPDLWKEMPLGSTPYQAYSDFLSKPTPR 262
            |.||.|..||.:.||..||.:|||:||.|.||..:|...|||..|....|
Yeast   204 TRTLENTLKAAFVAIGNTYGFLTPNLWAEQPLPVSPLDIYSDEASAQKKR 253

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS2	NP_001260303.1	uS5_euk_arch	37..245	CDD:273398	133/207 (64%)
		Ribosomal_S5	85..149	CDD:278748	46/63 (73%)
		Ribosomal_S5_C	168..235	CDD:281681	41/66 (62%)
RPS2	NP_011392.1	PTZ00070	31..252	CDD:240255	139/221 (63%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157346388
Domainoid	1	1.000	101	1.000	Domainoid score	I1551
eggNOG	1	0.900	-	-		E1_COG0098
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37714
Inparanoid	1	1.050	305	1.000	Inparanoid score	I492
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S217
OMA	1	1.010	-	-		QHG62203
OrthoFinder	1	1.000	-	-		FOG0001382
OrthoInspector	1	1.000	-	-		oto99745
orthoMCL	1	0.900	-	-		OOG6_100429
Panther	1	1.100	-	-	LDO	PTHR13718
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1244
SonicParanoid	1	1.000	-	-		X871
TreeFam	1	0.960	-	-
	16	15.740