DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment RpS2 and rps2

DIOPT Version :9

Sequence 1:	NP_001260303.1	Gene:	RpS2 / 34309	FlyBaseID:	FBgn0004867	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_998444.1	Gene:	rps2 / 406565	ZFINID:	ZDB-GENE-040426-2454	Length:	280	Species:	Danio rerio

Alignment Length:	268	Identity:	218/268 - (81%)
Similarity:	237/268 - (88%)	Gaps:	7/268 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADEAPARSGFRGGFGSRGGRG-----GRGRGRGRWARGRGKEDSKEWVPVTKLGRLVREGKIKS 60
            |||:|..|.|||||||: ||||     ||||||||.||| ||.:.|||||||||||||::.||||
Zfish     1 MADDAGGRGGFRGGFGT-GGRGRGRGRGRGRGRGRGARG-GKSEDKEWVPVTKLGRLVKDMKIKS 63

  Fly    61 LEEIYLYSLPIKEFEIIDFFLGSSLKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDNNGHIGLGVK 125
            |||||||||||||.|||||||||:|||||||||||||||||||||||||||||||.|||:|||||
Zfish    64 LEEIYLYSLPIKESEIIDFFLGSALKDEVLKIMPVQKQTRAGQRTRFKAFVAIGDYNGHVGLGVK 128

  Fly   126 CSKEVATAIRGAIILAKLSVVPVRRGYWGNKIGKPHTVPCKVTGKCGSVSVRLIPAPRGTGIVSA 190
            |||||||||||||||||||::|||||||||||||||||||||||:||||.|||||||||||||||
Zfish   129 CSKEVATAIRGAIILAKLSIIPVRRGYWGNKIGKPHTVPCKVTGRCGSVLVRLIPAPRGTGIVSA 193

  Fly   191 PVPKKLLTMAGIEDCYTSARGSTGTLGNFAKATYAAIAKTYAYLTPDLWKEMPLGSTPYQAYSDF 255
            |||||||.||||:||||||||.|.|||||||||:.||:|||:|||||||||.....:|||.::|.
Zfish   194 PVPKKLLMMAGIDDCYTSARGCTATLGNFAKATFDAISKTYSYLTPDLWKETVFTKSPYQEFTDH 258

  Fly   256 LSKPTPRL 263
            |:|...|:
Zfish   259 LAKTHTRV 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS2	NP_001260303.1	uS5_euk_arch	37..245	CDD:273398	183/207 (88%)
		Ribosomal_S5	85..149	CDD:278748	59/63 (94%)
		Ribosomal_S5_C	168..235	CDD:281681	56/66 (85%)
rps2	NP_998444.1	PTZ00070	40..264	CDD:240255	189/223 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595593
Domainoid	1	1.000	132	1.000	Domainoid score	I5097
eggNOG	1	0.900	-	-		E1_COG0098
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37714
Inparanoid	1	1.050	431	1.000	Inparanoid score	I1686
OMA	1	1.010	-	-		QHG62203
OrthoDB	1	1.010	-	-		D1197354at2759
OrthoFinder	1	1.000	-	-		FOG0001382
OrthoInspector	1	1.000	-	-		oto41773
orthoMCL	1	0.900	-	-		OOG6_100429
Panther	1	1.100	-	-	LDO	PTHR13718
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1244
SonicParanoid	1	1.000	-	-		X871
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800