DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment RpS2 and rps-2

DIOPT Version :9

Sequence 1:	NP_001260303.1	Gene:	RpS2 / 34309	FlyBaseID:	FBgn0004867	Length:	267	Species:	Drosophila melanogaster
Sequence 2:	NP_501322.1	Gene:	rps-2 / 177583	WormBaseID:	WBGene00004471	Length:	272	Species:	Caenorhabditis elegans

Alignment Length:	274	Identity:	201/274 - (73%)
Similarity:	220/274 - (80%)	Gaps:	19/274 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MADEAPARSGFRG----------------GFGSRGGRGGRGRGRGRWARGRGKEDSKEWVPVTKL 49
            |||....:|||.|                |.|.|||||||| |||..| |||.|...||.|||||
Worm     1 MADRGGFQSGFGGRGGGRGGARPAGDRPAGRGGRGGRGGRG-GRGGRA-GRGGEKETEWTPVTKL 63

  Fly    50 GRLVREGKIKSLEEIYLYSLPIKEFEIIDFFLGSSLKDEVLKIMPVQKQTRAGQRTRFKAFVAIG 114
            ||||:|.||.:||||||.||||||||||| .|.|:||||||||.||||||.||||||||||||||
Worm    64 GRLVKEKKITTLEEIYLNSLPIKEFEIID-ALCSNLKDEVLKISPVQKQTTAGQRTRFKAFVAIG 127

  Fly   115 DNNGHIGLGVKCSKEVATAIRGAIILAKLSVVPVRRGYWGNKIGKPHTVPCKVTGKCGSVSVRLI 179
            |:.||:||||||||||||||||||:.|||:||||||||||||||.||||||||||||.||.||||
Worm   128 DHAGHVGLGVKCSKEVATAIRGAIVAAKLAVVPVRRGYWGNKIGLPHTVPCKVTGKCASVMVRLI 192

  Fly   180 PAPRGTGIVSAPVPKKLLTMAGIEDCYTSARGSTGTLGNFAKATYAAIAKTYAYLTPDLWKEMPL 244
            ||||||||||||||||||.|||||||||:|:|||.||||||||||||:.:||:|||||||||..|
Worm   193 PAPRGTGIVSAPVPKKLLHMAGIEDCYTAAKGSTATLGNFAKATYAALQRTYSYLTPDLWKEEAL 257

  Fly   245 GSTPYQAYSDFLSK 258
            ..:|||.:.::|::
Worm   258 EKSPYQRHHEYLAR 271

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
RpS2	NP_001260303.1	uS5_euk_arch	37..245	CDD:273398	172/207 (83%)
		Ribosomal_S5	85..149	CDD:278748	55/63 (87%)
		Ribosomal_S5_C	168..235	CDD:281681	56/66 (85%)
rps-2	NP_501322.1	uS5_euk_arch	56..257	CDD:273398	171/201 (85%)
		Ribosomal_S5	98..162	CDD:278748	55/63 (87%)
		Ribosomal_S5_C	181..248	CDD:281681	56/66 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167039
Domainoid	1	1.000	133	1.000	Domainoid score	I3158
eggNOG	1	0.900	-	-		E1_COG0098
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37714
Inparanoid	1	1.050	383	1.000	Inparanoid score	I1180
Isobase	1	0.950	-	0.928771	Normalized mean entropy	S217
OMA	1	1.010	-	-		QHG62203
OrthoDB	1	1.010	-	-		D1197354at2759
OrthoFinder	1	1.000	-	-		FOG0001382
OrthoInspector	1	1.000	-	-		oto18660
orthoMCL	1	0.900	-	-		OOG6_100429
Panther	1	1.100	-	-	LDO	PTHR13718
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1244
SonicParanoid	1	1.000	-	-		X871
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790