Protein Alignment nAChRalpha6 and LOC798522

DIOPT Version :9

• Sequence 1: NP_995675.1
• Gene: nAChRalpha6 / 34304
• FlyBaseID: FBgn0032151
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_001338964.6
• Gene: LOC798522 / 798522
• -ID: -
• Length: 488
• Species: Danio rerio
• Alignment Length: 530
• Identity: 172/530 - (32%)
• Similarity: 283/530 - (53%)
• Gaps: 81/530 - (15%)

  Fly    13 VLLIFLAIIKES---CQGPHEKRLLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQ 74
            |:|:...::.|:   .||....:|||.|:..|::..|||.:..:.|.|...:||.||.|:||:||
Zfish    10 VMLLSALLLAEASHCAQGRFAHKLLNDLMEDYSSALRPVDDTDKSLNVTLQVTLSQIKDMDERNQ 74

  Fly    75 ILTTNAWLNLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHN 139
            :|....|:...|:|.:|:|::.:|.|::.:||..:.:|:||:::||.||:.|.|...||:|:::.
Zfish    75 VLIAYLWIRQVWHDAHLKWSKEDYDGLEVIRIPSSLIWRPDLVLYNKADDDFSGPVDTNVVLRYT 139

  Fly   140 GSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITNGEWY 204
            |...:..|.|.||:|.:|:::||||.|.|.:.||||||:|||:|:.:.|. .||||||:.|.||.
Zfish   140 GEITWDAPAITKSSCVVDVSYFPFDSQQCNLTFGSWTYNGNQVDIAMGSV-SGDLSDFVENVEWE 203

  Fly   205 LLAMPGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKL 269
            ...||..||.|:|.||.:||.|||:|:.::||:.:|..||::||.|||.:|.|.|.||.|||||:
Zfish   204 CHGMPATKNVIMYGCCSDPYPDITYTVLLQRRSSFYIINLLLPCFLISFLAPLSFYLPADSGEKV 268

  Fly   270 TLGVTILLSLTVFLNLVAESMPTTSDAVPLIGVTILLSLTVFLNLVAETLPQVSDAIPLLGTYFN 334
            :||||:||:||||..:||||||.                              |:::||:..|:.
Zfish   269 SLGVTVLLALTVFQMMVAESMPP------------------------------SESVPLIAKYYI 303

  Fly   335 CIMFMVASSVVLTVVVLNYHHRTADIHEMPPWIKSVFLQWLP---WILRMGRP-----GRKITRK 391
            ..|.|:.:|..||:.::|.|...|:...:|.|.|.:.:.::.   ::..:|..     |:....:
Zfish   304 ATMTMITASTALTIFIMNIHFCGAEAKPVPYWAKVLIIDYMSKIFFVYEVGESCASPFGQAEESE 368

  Fly   392 TILLSNRMKELELKERSSKSLLANVLDIDDDFRHTISGSQTAIGSSASFGRPTTVEEH------- 449
            :....|..::.:|.....|                ||||..          |...|:|
Zfish   369 SFHSQNHHRKHKLHHPKGK----------------ISGSPP----------PCCPEDHKSPFVLG 407

  Fly   450 -HTAIGCNHKDLHL-----ILKELQFITARMRKADDEAELIGDWKFAAMVVDRFCLIVFTLFTII 508
             .:.:.|..:..:|     :|:.:::|....|:....|..:.:||..|.|:|||.:.:|.:...:
Zfish   408 CESCVYCGFRSGNLACDTKLLRNVEYIANCFREQKTTALKVAEWKKVAKVMDRFFMWIFFIMVFL 472

  Fly   509 ATVTVLLSAP 518
            .::.::..||
Zfish   473 MSILIIGKAP 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha6	NP_995675.1	LIC	11..517	CDD:273305	170/527 (32%)
		LGIC_ECD_nAChR	55..236	CDD:349798	80/180 (44%)
LOC798522	XP_001338964.6	Neur_chan_LBD	32..477	CDD:332142	165/501 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D363540at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.920