Protein Alignment nAChRalpha6 and lgc-24

DIOPT Version :9

• Sequence 1: NP_995675.1
• Gene: nAChRalpha6 / 34304
• FlyBaseID: FBgn0032151
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001123110.2
• Gene: lgc-24 / 6418837
• WormBaseID: WBGene00045385
• Length: 389
• Species: Caenorhabditis elegans
• Alignment Length: 324
• Identity: 72/324 - (22%)
• Similarity: 115/324 - (35%)
• Gaps: 64/324 - (19%)

  Fly    32 RLLNHLLSTYNTLERPVAN----ESEP-LEVKFGLTLQQIIDVDEKNQILTTNAWLNLEWNDYNL 91
            :|.:.|...||. ..||..    |:.| |||.|    ...||.|.....:..||  .|.|.|..|
 Worm    30 KLRSDLFKNYNG-SMPVGKGEYLEATPSLEVGF----IHFIDDDHGFMSVVINA--ELTWIDERL 87

  Fly    92 RWNETEYGGVKDL-------RITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGSCLYVPPGI 149
            :||...|.||:::       | ..|..|.| ::.|.|.|..:.   ..:::...:...|....|.
 Worm    88 KWNPANYSGVREIVEKTFEFR-KDNNCWMP-IVKYRSYDRRYS---ELDLLEFSDARTLISYKGE 147

  Fly   150 FKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFIT-NG------------ 201
            .|:..:..:|      ..|:..||.:..|.....::|......|...|:: ||
 Worm   148 IKTALQTMVT------TKCQFSFGEYPNDYQNCSIMLIPNQNADEFRFVSPNGYCNPKFENLEHR 206

  Fly   202 --EWYLLAMPGKKNTIVYACCPEPY-------------VDITFTIQIRRRTLYYFFNLIVPCVLI 251
              ..:.|.:.|.::.|.|......:             .:..|.:..:|........|.:|.:||
 Worm   207 AVRVHDLHLMGVESNIFYTFANTYFTAEEVTGFEYMAKTEFRFNLMFKRVNKLLNVKLSIPSILI 271

  Fly   252 SSMALLGFTLPPDSGEKLTLGVTILLSLTVFLNL-VAESMPTTSDAVPLIGVTILLSL--TVFL 312
            |...::....|  :|..: .|......:.|...| |::.:|.....:|..|...|..|  ||||
 Worm   272 SMFLIIAGLFP--NGYSI-FGYAYCFFVEVMHGLYVSKILPNDIRGIPYHGALALCFLIETVFL 332

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha6	NP_995675.1	LIC	11..517	CDD:273305	72/324 (22%)
		LGIC_ECD_nAChR	55..236	CDD:349798	43/215 (20%)
lgc-24	NP_001123110.2	LGIC_ECD	62..226	CDD:355788	38/176 (22%)
		Cys-loop	160..174	CDD:349787	4/13 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910