Protein Alignment nAChRalpha6 and alka

DIOPT Version :10

• Sequence 1: NP_995675.1
• Gene: nAChRalpha6 / 34304
• FlyBaseID: FBgn0032151
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_610619.2
• Gene: alka / 36145
• FlyBaseID: FBgn0033558
• Length: 449
• Species: Drosophila melanogaster
• Alignment Length: 362
• Identity: 71/362 - (19%)
• Similarity: 124/362 - (34%)
• Gaps: 105/362 - (29%)

  Fly    46 RPVANESEPLEVKFGLTLQQIIDVDEKNQILTTNAWLNLEWNDYNL------RWNETEYGGVKDL 104
            ||.:.:..|:.|.|.:.   ::|::.          :|:|..|:.:      ||.|:......|:
  Fly    49 RPPSKKGSPVIVDFSIF---VVDINS----------INVEDMDFRVDMFIHQRWLESRLEIPDDI 100

  Fly   105 --------RITP---NKLWKPDVLMYNSADEGFDGTYH--TNIVVKHNGSCLYVPPGIFKSTCKI 156
                    .:.|   ...|:||....||.........|  |::.:..|.:..|.........|::
  Fly   101 FEEGDDYVTLLPEVFENFWQPDPYFLNSKIAEIATLTHKFTSVTLYKNKTVRYAARMHAIIACQM 165

  Fly   157 DITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFIT-NGEWYLLA------------- 207
            :...:|.|.|.|.:...|  :..|...:.|...|.|     :| |.|..||.
  Fly   166 EFQLYPMDIQVCPIYIES--FSSNNQKVKLRWSDSG-----VTLNPELKLLQYNLGQPLELEESD 223

  Fly   208 --MPGKKNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDS-GEKL 269
              ||.|...         :..:|...:..|:..::......|..|:..::...|.|..|: ..::
  Fly   224 GYMPEKVGN---------FSRLTVYFRFERQIGHHLIQTFAPSSLVVMLSWFSFWLGLDAIPGRV 279

  Fly   270 TLGVTILLSLTVFLNLVAESMPTTSDAVPLIGVTIL------LSLTVFLNLVAETLPQVSDAIPL 328
            ||.||.:|:|.        :|.|.:|..|:..|..|      ..|:||..|
  Fly   280 TLLVTCMLTLV--------TMFTGADIPPVAYVKALDLWMAGCMLSVFAAL-------------- 322

  Fly   329 LGTYFNCIMFMVASSVVLTVVVLNYHHRTADIHEMPP 365
                        |..||:.|:.:.|.::...|.::.|
  Fly   323 ------------AEFVVVKVLDVQYQYQVNRIPKVLP 347

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha6	NP_995675.1	LIC	11..517	CDD:455710	71/362 (20%)
		LGIC_ECD_nAChR	55..236	CDD:349798	39/215 (18%)
		Cys-loop	154..168	CDD:349798	4/13 (31%)
alka	NP_610619.2	LIC	8..441	CDD:455710	71/362 (20%)