Protein Alignment nAChRalpha6 and pbo-6

DIOPT Version :9

• Sequence 1: NP_995675.1
• Gene: nAChRalpha6 / 34304
• FlyBaseID: FBgn0032151
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: NP_001294833.1
• Gene: pbo-6 / 24104421
• WormBaseID: WBGene00017375
• Length: 422
• Species: Caenorhabditis elegans
• Alignment Length: 388
• Identity: 107/388 - (27%)
• Similarity: 181/388 - (46%)
• Gaps: 75/388 - (19%)

  Fly     9 LSLFVLL----IFLAIIKESCQGPHEKRLLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDV 69
            |::|:.:    :.:|...|..|| ...||..|||..:|....|...    :::...:.|..||.:
 Worm     6 LTIFIFITTVTVGVAEFSEQYQG-SSSRLTRHLLEKHNKCSPPDGR----VDISHNIELVHIIGI 65

  Fly    70 DEKNQILTTNAWLNLEWNDYNLRWNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYH--- 131
            :|.||.:....::..:|.|.:|.|...|:.|:|...:..:.:|.||::::|:.:       |
 Worm    66 NELNQNMQVLVYIVQQWTDASLSWKVEEFRGIKHTWLPEHSIWIPDIIVFNTLE-------HKML 123

  Fly   132 -----TNIVVKHNGSCLYVPPGIFKSTCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDG 191
                 :.|.|.:.|...|..|.|:...|:|.|..||||||.|:::|.||.||.::  ::||:...
 Worm   124 LEAVRSPIKVSYTGEVTYAYPAIYTVLCQIGIATFPFDDQVCKIRFASWAYDEDK--ILLNASHK 186

  Fly   192 GDLSDFITNGEWYL--LAMPGK----KNTIVYACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVL 250
            ..|.::..|.||.|  :.|..|    :.|:|        .:|.:.|::.|:..||..:|:||..:
 Worm   187 PLLKNYSPNEEWALQDVDMARKEYEHEETVV--------SEIIYYIKVARKPFYYLISLVVPSYI 243

  Fly   251 ISSMALLG----FTLPPDSGEKLTLGVTILLSLTVFLNLVAESMPTTSDAVPLIGVTILLSLTVF 311
            |..:::.|    |:...:..|:.|||||.:||:.|                        |||
 Worm   244 ICVLSIAGLFARFSTKHERQERFTLGVTAILSMAV------------------------LSL--- 281

  Fly   312 LNLVAETLPQVSDAIPLLGTYFNCIMFMVASSVVLTVVVLNYHHRTADIHEMPP--WIKSVFL 372
              :|.|.:|..|:.:|||..|.:.|:.||..:.:||..|:..|.:....|.:.|  ||:.|.|
 Worm   282 --VVTEKVPHSSENVPLLIVYMHFIIVMVTIATILTSTVMRVHAKGFRTHFLSPPNWIRKVLL 342

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha6	NP_995675.1	LIC	11..517	CDD:273305	106/386 (27%)
		LGIC_ECD_nAChR	55..236	CDD:349798	52/194 (27%)
pbo-6	NP_001294833.1	Neur_chan_LBD	31..230	CDD:280998	60/219 (27%)
		Neur_chan_memb	264..>342	CDD:280999	32/106 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR18945
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010