Protein Alignment nAChRalpha6 and chrna10

DIOPT Version :9

• Sequence 1: NP_995675.1
• Gene: nAChRalpha6 / 34304
• FlyBaseID: FBgn0032151
• Length: 523
• Species: Drosophila melanogaster
• Sequence 2: XP_031753261.1
• Gene: chrna10 / 100487976
• -ID: -
• Length: 501
• Species: Xenopus tropicalis
• Alignment Length: 521
• Identity: 183/521 - (35%)
• Similarity: 286/521 - (54%)
• Gaps: 70/521 - (13%)

  Fly    23 ESCQGPHEKRLLNHLLSTYNTLERPVANESEPLEVKFGLTLQQIIDVDEKNQILTTNAWLNLEWN 87
            :..||....:|:|.|.:.|:...|||.:..:.:.|...:||.||||:||:||||....|:...|.
 Frog    18 QGAQGRFAYKLMNDLFANYSNALRPVEDMDKAMNVTLQVTLSQIIDMDERNQILMAYLWIRQVWF 82

  Fly    88 DYNLRWNETEYGGVKDLRITPNKLWKPDVLMYNSADEGFDGTYHTNIVVKHNGSCLYVPPGIFKS 152
            |..||||:.:|.|:..:||..:.:|:||:::||:||:.|.|:..||:|::::|..::..|.|.||
 Frog    83 DAYLRWNKEDYDGLDTIRIPSSYVWRPDIVLYNNADDQFTGSMETNVVIRYDGQIMWDSPAITKS 147

  Fly   153 TCKIDITWFPFDDQHCEMKFGSWTYDGNQLDLVLNSEDGGDLSDFITNGEWYLLAMPGKKNTIVY 217
            :||:|:::||||.|.|.:.||||||:|||:| :||..|.|||:||:.|.||.:|.||.||:.|.|
 Frog   148 SCKVDVSFFPFDGQQCRLTFGSWTYNGNQID-ILNHLDTGDLTDFVENVEWEILGMPAKKSVITY 211

  Fly   218 ACCPEPYVDITFTIQIRRRTLYYFFNLIVPCVLISSMALLGFTLPPDSGEKLTLGVTILLSLTVF 282
            .||.|||.|:|:|:.::||..:|.|||::|||:||.:|.|||.||.|||||::||||:||:||||
 Frog   212 GCCSEPYPDVTYTLILKRRASFYIFNLLLPCVMISFLAPLGFYLPADSGEKVSLGVTVLLALTVF 276

  Fly   283 LNLVAESMPTTSDAVPLIGVTILLSLTVFLNLVAETLPQVSDAIPLLGTYFNCIMFMVASSVVLT 347
            ..|||||||.                              |:.:||:|.|:...|.|:.:|..||
 Frog   277 QLLVAESMPP------------------------------SENVPLIGKYYIATMTMITASTALT 311

  Fly   348 VVVLNYHHRTADIHEMPPWIKSVFLQWLP---WILRMG----------RPGRKITRKTILLSNRM 399
            :.::|.||...:...:|.|.|...||::.   ::..:|          .|..:.|.|...:..:.
 Frog   312 IFIMNIHHCGPEAKPVPQWAKKFILQYMSRIFFVYEVGESCRRPRTEPEPNSERTSKVPGIDGQA 376

  Fly   400 K-------------ELELKERSSKSLLANVLDIDDDFRHTISGSQTAIGSSASFGRPTTVEE--- 448
            |             :|..|::.:|..|.:     ..:.|:....:..:......|:....||
 Frog   377 KREDIADVVKDCPEKLSPKDKEAKEELEH-----SKYAHSQESGKYYVSEQGGVGKGFGYEECPK 436

  Fly   449 HHTAIGCNHKDLHLILKELQFITARMRKADDEAELIGDWKFAAMVVDRFCLIVFTLFTIIATVTV 513
            .|..  |:::.|   ||.:::|....|......:..|:||..|.|:|||.:.||.:...:.:|.:
 Frog   437 IHCL--CHNERL---LKNIEYIANCFRDQRATQKRTGEWKKVAKVMDRFFMWVFFIMVFLMSVLI 496

  Fly   514 L 514
            :
 Frog   497 M 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
nAChRalpha6	NP_995675.1	LIC	11..517	CDD:273305	183/521 (35%)
		LGIC_ECD_nAChR	55..236	CDD:349798	86/180 (48%)
chrna10	XP_031753261.1	LIC	27..496	CDD:273305	181/509 (36%)
		LGIC_ECD_nAChR_A10	50..230	CDD:349824	86/180 (48%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D363540at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920