Protein Alignment IP3K1 and IP6K1

DIOPT Version :9

• Sequence 1: NP_609313.2
• Gene: IP3K1 / 34300
• FlyBaseID: FBgn0032147
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001229758.1
• Gene: IP6K1 / 9807
• HGNCID: 18360
• Length: 441
• Species: Homo sapiens
• Alignment Length: 389
• Identity: 83/389 - (21%)
• Similarity: 150/389 - (38%)
• Gaps: 140/389 - (35%)

  Fly    76 VEQQQQQQQQQQSNNNNERIPNENCDYLSLQRSGQAPKNHIQAQDPAQMSLLKFLAINALELSAP 140
            |||....:::|....::.|         ||.|||.. .:|  .::.|.:|
Human   102 VEQDDTTEREQPRRKHSRR---------SLHRSGSG-SDH--KEEKASLS--------------- 139

  Fly   141 ATPHLLQHQQAHKQAK-PQGWMQLSGH---PESIVPTSTGIVRKRISGLEDSEVHAYRLICKEPQ 201
                 |:..::.::|| |:  ::|..|   |..::..::|:..::||.      :.:.|.|.:.|
Human   140 -----LETSESSQEAKSPK--VELHSHSEVPFQMLDGNSGLSSEKISH------NPWSLRCHKQQ 191

  Fly   202 TAQIVPAYFGIQEMQSQ-------HFIELQDLLAGFRDPCVMDIKMGSRTFLESEVSNATLRPDL 259
                      :..|:|:       .|:.|::::..|:.|||:|:|||:|
Human   192 ----------LSRMRSESKDRKLYKFLLLENVVHHFKYPCVLDLKMGTR---------------- 230

  Fly   260 YQKMIAVDAGAPTPAEHEARAITKLRYMTFRESLSSSHSKGFRIEALRLRGRPPVKDLKT----C 320
                   ..|....||..||.:.|...       |:|.:.|.|:..::      |..|.|    |
Human   231 -------QHGDDASAEKAARQMRKCEQ-------STSATLGVRVCGMQ------VYQLDTGHYLC 275

  Fly   321 R--------SSEQIAQTIEQF----LAARRSVQKELLKRLKHMRLVIEQSTFFASHEIIGSSIFI 373
            |        |.|.....:.|:    |..||.:.:.:|.:|:.::.|:|:.   ||:....||:.:
Human   276 RNKYYGRGLSIEGFRNALYQYLHNGLDLRRDLFEPILSKLRGLKAVLERQ---ASYRFYSSSLLV 337

  Fly   374 VYDDDRVGVWLIDFAKCRELPPHVRVDHRSAWAPGNREEGLLRGMDELIRSFEEVYARCGSHRS 437
            :||.          .:||   ....:|.||        |..|:.:|.::   .||.:.||...|
Human   338 IYDG----------KECR---AESCLDRRS--------EMRLKHLDMVL---PEVASSCGPSTS 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IP3K1	NP_609313.2	IPK	220..426	CDD:281727	50/221 (23%)
IP6K1	NP_001229758.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	100..175		21/106 (20%)
		IPK	207..434	CDD:281727	55/234 (24%)
		Substrate binding. /evidence=ECO:0000250	220..228		5/7 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	370..392		3/8 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151385
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840