Protein Alignment IP3K1 and Ip6k2

DIOPT Version :9

• Sequence 1: NP_609313.2
• Gene: IP3K1 / 34300
• FlyBaseID: FBgn0032147
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001366530.1
• Gene: Ip6k2 / 76500
• MGIID: 1923750
• Length: 448
• Species: Mus musculus
• Alignment Length: 511
• Identity: 92/511 - (18%)
• Similarity: 171/511 - (33%)
• Gaps: 174/511 - (34%)

  Fly     1 MTMTSTVLQRPIQAKPEKKASSKSTSSSRSRSTMAWSNEKLRFSCIDNIGLKQLWKLIALDTSAS 65
            :....|.|.:|:  .|.:....::..:...|.|..:....:...|.|..|         ...:..
Mouse    33 LRFNETTLCKPL--VPREHQFYETLPAEMRRFTPQYKAVLIFVRCADEFG---------ASGNIE 86

  Fly    66 SKQRSAMMLEVEQQQQQQ------QQQQSNNNNERIPNENCDYLSLQRSGQAPKNHIQAQDPAQM 124
            :|::..:.:..|:.:.:.      ..:..:...:.:.|.:|:..|........|:|
Mouse    87 TKEQGVVSVRFEEDEDRNLCLIAYPLKGDHGTVDIVDNSDCEPKSKLLRWTNKKHH--------- 142

  Fly   125 SLLKFLAINALELSAPATPHLLQHQ-----QAHKQAKPQGWMQLSGHPESIVPTSTGIVRKRISG 184
                     |||........:.||:     ::||..:...|::.|    .::..|   |.|:  |
Mouse   143 ---------ALETEKNPKDWVRQHRKEEKMKSHKLEEEFEWLKKS----EVLYYS---VEKK--G 189

  Fly   185 LEDSEVHAYR---LICKEPQTAQIVPAYFGIQEMQ--SQH-----FIELQDLLAGFRDPCVMDIK 239
            ...|::..|.   :.|.:.|          :|.|:  ::|     ||.|::|.:.:..|||:|:|
Mouse   190 NVSSQLKHYNPWSMKCHQQQ----------LQRMKENAKHRNQYKFILLENLTSRYEVPCVLDLK 244

  Fly   240 MGSRTFLESEVSNATLRPDLYQKMIAVDAGAPTPAEHEARAITKLRYMTFRESLSSSHSKGFRIE 304
            ||:|                       ..|.....|..|..|.|.:.       |:|...|.|:.
Mouse   245 MGTR-----------------------QHGDDASEEKAANQIRKCQQ-------STSAVIGVRVC 279

  Fly   305 ALRL--------------RGRPPVKDLKTCRSSEQIAQTIEQFLAARRSVQKEL----LKRLKHM 351
            .:::              .||.        .|.:...:.:.||....|.:::||    ||:|..:
Mouse   280 GMQVYQAGTGQLMFMNKYHGRK--------LSVQGFKEALFQFFHNGRYLRRELLGPVLKKLTEL 336

  Fly   352 RLVIEQSTFFASHEIIGSSIFIVYD------------------------DDRVGVW--------- 383
            :.|:|:.   .|:....||:.::||                        |:..|.:
Mouse   337 KAVLERQ---ESYRFYSSSLLVIYDGKEWPEVTLDSDAEDLEDLSEESADESAGAYAYKPIGASS 398

  Fly   384 ----LIDFA--KCRELPPHVRVDHRSAWAPGNREEGLLRGMDELIRSFEEVYARCG 433
                :||||  .|| |.....|.|.      .::.|.:.|:..||....|:....|
Mouse   399 VDVRMIDFAHTTCR-LYGEDSVVHE------GQDAGYIFGLQSLIDIVTEISEESG 447

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IP3K1	NP_609313.2	IPK	220..426	CDD:281727	54/262 (21%)
Ip6k2	NP_001366530.1	IPK	225..440	CDD:397715	54/262 (21%)
		Substrate binding. /evidence=ECO:0000250	238..246		5/7 (71%)
		Substrate binding. /evidence=ECO:0000250|UniProtKB:Q8NFU5	258..265		2/6 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167841518
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.840