Protein Alignment IP3K1 and IP6K3

DIOPT Version :9

• Sequence 1: NP_609313.2
• Gene: IP3K1 / 34300
• FlyBaseID: FBgn0032147
• Length: 441
• Species: Drosophila melanogaster
• Sequence 2: NP_001136355.1
• Gene: IP6K3 / 117283
• HGNCID: 17269
• Length: 410
• Species: Homo sapiens
• Alignment Length: 373
• Identity: 73/373 - (19%)
• Similarity: 140/373 - (37%)
• Gaps: 117/373 - (31%)

  Fly   117 QAQDPAQMS-----------LLKFLAINALELSAPATPHLLQHQQAHKQAKPQGWMQLSGHPE-- 168
            ::|:|.::|           |.:....|..:.:....|| .|..::.|::..:..::...|..
Human    90 ESQEPFKVSTESAAVAIWQTLQQTTGSNGSDCTLAQWPH-AQLARSPKESPAKALLRSEPHLNTP 153

  Fly   169 --SIVPTSTG--IVRKRIS--GLEDSEVHAYRLICKEPQTAQIVPAYFGIQEMQSQHFIELQDLL 227
              |:|..:.|  :.||..:  ||:..:.|..||..:.|             |.:...|:.|::::
Human   154 AFSLVEDTNGNQVERKSFNPWGLQCHQAHLTRLCSEYP-------------ENKRHRFLLLENVV 205

  Fly   228 AGFRDPCVMDIKMGSRTFLESEVSNATLRPDLYQKMIAVDAGAPTPAEHEARAITKLRYMTFRES 292
            :.:..|||:|:|||:|                       ..|.....|.:||.:.|.       :
Human   206 SQYTHPCVLDLKMGTR-----------------------QHGDDASEEKKARHMRKC-------A 240

  Fly   293 LSSSHSKGFRIEALRLRGRPPVKDLKTCR--------SSEQIAQTIEQFLAARRSVQKELLKRLK 349
            .|:|...|.||..:::....  |....|:        |.|...|.:.|||.....:::|||:.:.
Human   241 QSTSACLGVRICGMQVYQTD--KKYFLCKDKYYGRKLSVEGFRQALYQFLHNGSHLRRELLEPIL 303

  Fly   350 H-MRLVIEQSTFFASHEIIGSSIFIVYDDD----------------------------RVGVWLI 385
            | :|.::......:|:....||:.::||..                            :|.:.:|
Human   304 HQLRALLSVIRSQSSYRFYSSSLLVIYDGQEPPERAPGSPHPHEAPQAAHGSSPGGLTKVDIRMI 368

  Fly   386 DFAKCRELPPHVRV-----DHRSAWAPGNREEGLLRGMDELIRSFEEV 428
            |||       |...     :|.:...|   :.|.:.|::.|||..:::
Human   369 DFA-------HTTYKGYWNEHTTYDGP---DPGYIFGLENLIRILQDI 406

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
IP3K1	NP_609313.2	IPK	220..426	CDD:281727	51/247 (21%)
IP6K3	NP_001136355.1	IPK	198..404	CDD:309046	51/247 (21%)
		Substrate binding. /evidence=ECO:0000250	211..219		5/7 (71%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	333..358		0/24 (0%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151384
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.840