Protein Alignment ppk11 and scnn1b

DIOPT Version :10

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001072437.1
• Gene: scnn1b / 779891
• XenbaseID: XB-GENE-949109
• Length: 646
• Species: Xenopus tropicalis
• Alignment Length: 652
• Identity: 121/652 - (18%)
• Similarity: 217/652 - (33%)
• Gaps: 260/652 - (39%)

  Fly    46 LYRNLKRLKILRWYNRVSKRFEEFPLPKFLGFLQARNDDGLCKRKTGFEI---YCEMASIHGFHI 107
            |:..:||||  |::.|...|.::.|     |:             |..|:   :|:..:.||...
 Frog     2 LHVKMKRLK--RYFTRALHRIQKGP-----GY-------------TYKELLVWFCDNTNTHGPKR 46

  Fly   108 FVGAKTWQRILWWLLIC----------NAVLLSFTLVIMSLSMSKETPTIRFIDTMMKPTAEVPF 162
            .:.....:|::|::|..          ..::|::....:|:|:|....|:.             |
 Frog    47 IIKEGPKKRVMWFILTLVFAGLVFWQWGVLILTYLSYGVSVSLSIGFKTME-------------F 98

  Fly   163 PAVTICG----------------------------FNTKEWMN---------------------- 177
            ||||:|.                            |::::..|
 Frog    99 PAVTVCNANPYKYSRVKPLLKDLDALVATALDRIQFSSQDQANTFTQSSTNQNVTLDPTLWNHIP 163

  Fly   178 ---------SSQIVN---------QRNASWLELLED---------LALPICPQ------------ 203
                     |:.|||         .:|.|:....||         :|:.:|..
 Frog   164 LVVIDETDPSNPIVNNIFDNNAIYSKNNSFRNSSEDQTSYSQRYKVAMKLCTNNNTQCVYRNFTS 228

  Fly   204 -IKICQ-W------------------------DNRMVNCLDQLQP--------IWTLDQRLCCSF 234
             |:..| |                        ::.::.||...||        |:..|...|..|
 Frog   229 GIQALQEWYLLQLSSIFSNVPLADRIAMGFKAEDLILTCLFGGQPCSYRNFTRIYDADYGNCYIF 293

  Fly   235 NYNKQ----LFSSYLGVSFVLRSNDEILQS------SKSAGFEVLIHESHEIPNGATPRVF-VPG 288
            |:.::    :.|:..|..|.|:...:|.|.      ..:|...:::|:....|......:: :||
 Frog   294 NWGQEGEDPMASANPGADFGLKLVLDIEQGEYLPYVQTTAAARLILHQQRSFPFVKDLGIYAMPG 358

  Fly   289 ESDAHIML--------RPYINRFTKNLKGLSLQKRGCYFSTERRLILSDVYNQINCLAECRTESI 345
            ...:..:|        .|| :..|.|...:.:|.....|::.        |:..:||..|..|.:
 Frog   359 TETSIAVLVDQLEHMEAPY-SSCTVNGSDIPVQNLYAEFNSS--------YSIQSCLRSCYQEQM 414

  Fly   346 LKSCGCIPPKSPIEK-----------SWLICDLKQMQCVIDFDHDEIISGEQKNCD--CLPPCEF 397
            :::|||...:.|:..           .|:.|.......|.|          :::|.  |..||..
 Frog   415 VQTCGCADYQYPLPNGSEYCSNDKYPDWVPCYYGLRDSVAD----------RESCISLCQQPCND 469

  Fly   398 NRYEF---QSD-------------IRFIKGMINNSIVNTSNQETTNEVRVRVYYDS----AIAEE 442
            .:|:.   .:|             :.:.|...:|..||.:     ..||:.:|:..    :|.|.
 Frog   470 TQYKMVISMADWPSAGAQDWIFHVLSYEKDSSHNITVNRN-----GIVRLNIYFQEFNYRSITES 529

  Fly   443 LLLDVYENWLTFIGTFGGITGLFMGCSFVSVFEL--IFFSCVRPTCNWLTRQQIL-W---RRRRN 501
            ...:|.  ||  :...||..|.:||.|.:.:.|.  |...||     |:|..::| |   ||:|.
 Frog   530 EATNVV--WL--LSNLGGQFGFWMGGSVLCIIEFGEIIIDCV-----WITILKLLAWIKDRRQRR 585

  Fly   502 QR 503
            ||
 Frog   586 QR 587

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	ASC	96..479	CDD:459966	98/569 (17%)
scnn1b	NP_001072437.1	ENaC	27..632	CDD:273304	111/607 (18%)