Protein Alignment ppk11 and SCNN1B

DIOPT Version :9

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_016879014.1
• Gene: SCNN1B / 6338
• HGNCID: 10600
• Length: 659
• Species: Homo sapiens
• Alignment Length: 592
• Identity: 102/592 - (17%)
• Similarity: 184/592 - (31%)
• Gaps: 237/592 - (40%)

  Fly    96 YCEMASIHGFHIFVGAKTWQRILWWLLICNAVLLSFTLVI----------------MSLSMSKET 144
            ||:..:.||....:.....::.:|:||    .||...||.                :|||:..:|
Human    48 YCDNTNTHGPKRIICEGPKKKAMWFLL----TLLFAALVCWQWGIFIRTYLSWEVSVSLSVGFKT 108

  Fly   145 PTIRFIDTMMKPTAEVPFPAVTIC----------------------------------------G 169
                           :.|||||||                                        .
Human   109 ---------------MDFPAVTICNASPFKYSKIKHLLKDLDELMEAVLERILAPELSHANATRN 158

  Fly   170 FNTKEWMNSSQI-VNQRNASW---LELLED---------------------LALPIC-------- 201
            .|...|.::..: :::||...   |:|..|                     :|:.:|
Human   159 LNFSIWNHTPLVLIDERNPHHPMVLDLFGDNHNGLTSSSASEKICNAHGCKMAMRLCSLNRTQCT 223

  Fly   202 --------------------------PQIKICQW----DNRMVNCLDQLQP--------IWTLDQ 228
                                      ||.::.:.    :..::.||...:|        |:....
Human   224 FRNFTSATQALTEWYILQATNIFAQVPQQELVEMSYPGEQMILACLFGAEPCNYRNFTSIFYPHY 288

  Fly   229 RLCCSFNY---NKQLFSSYLGVSFVLR------SNDEILQSSKSAGFEVLIHESHEIPNGATPRV 284
            ..|..||:   .|.|.|:..|..|.|:      ..|.:...:.:||..:::||....|
Human   289 GNCYIFNWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGVRLMLHEQRSYP------- 346

  Fly   285 FVPGESDAHIMLRPYINRFTKNLKGL---SLQKRGCYFS----TERRLILSDVYNQIN------- 335
            |:..|.       .|....|:...|:   .||:.|..:|    ....:.:.:.|:..|
Human   347 FIRDEG-------IYAMSGTETSIGVLVDKLQRMGEPYSPCTVNGSEVPVQNFYSDYNTTYSIQA 404

  Fly   336 CLAECRTESILKSCGCIPPKSPIEKSWLICDLKQM----QCVIDFDHDEIISGEQKNC--DCLPP 394
            ||..|..:.::::|.|.....|:.:....|:.:..    .|..|.   ::...:::.|  .|...
Human   405 CLRSCFQDHMIRNCNCGHYLYPLPRGEKYCNNRDFPDWAHCYSDL---QMSVAQRETCIGMCKES 466

  Fly   395 CEFNRY-----------EFQSDIRFIKGMINNSIVNTSNQETTN-------EVRVRVYYDS---- 437
            |...:|           |...|..|       .:::....::||       .|::.:|:..
Human   467 CNDTQYKMTISMADWPSEASEDWIF-------HVLSQERDQSTNITLSRKGIVKLNIYFQEFNYR 524

  Fly   438 AIAEELLLDVYENWLTFIGTFGGITGLFMGCSFVSVFEL--IFFSCVRPTCNWLTRQQIL----- 495
            .|.|....::.  ||  :...||..|.:||.|.:.:.|.  |....|     |:|..:::
Human   525 TIEESAANNIV--WL--LSNLGGQFGFWMGGSVLCLIEFGEIIIDFV-----WITIIKLVALAKS 580

  Fly   496 WRRRRNQ 502
            .|:||.|
Human   581 LRQRRAQ 587

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152143
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	88	1.000	Inparanoid score	I5132
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.790