Protein Alignment ppk11 and asic4b

DIOPT Version :10

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_999951.1
• Gene: asic4b / 407667
• ZFINID: ZDB-GENE-040513-6
• Length: 558
• Species: Danio rerio
• Alignment Length: 475
• Identity: 105/475 - (22%)
• Similarity: 184/475 - (38%)
• Gaps: 125/475 - (26%)

  Fly    83 DDGLCKRKTG---FEIYCEMASIHGFHIFVGAKT---WQRILWWLLICNAVLLSFTLVIMSLSMS 141
            |:||.::|.|   ...:...:|:||....:|...   :::.||.|    |:|:|..|.:...:.|
Zfish    31 DEGLRRQKEGMADLASFASSSSLHGLARALGTSERLGFRQTLWGL----ALLVSLGLFLYQATWS 91

  Fly   142 KETPTIR-FIDTMMKPT-AEVPFPAVTICGFNTKEW--MNSSQIVNQRNASWL-----------E 191
            ..|...| .:..:.:.| .|:.|||:|:|..|...:  :..:.|.:..|.:.|           |
Zfish    92 AATYLERPHLAALREETRRELTFPAITLCNVNRFRFSALTDADIYHLANLTGLPPKSRKGHRPSE 156

  Fly   192 L-----------------LEDLALPICPQIKICQWDNRMVNC-LDQLQPIWTLDQRLCCSFNYNK 238
            |                 |||:       :|.|.:..:  || .:....::|...: |.:||.||
Zfish   157 LQYPPPNMLDIFQRTGHQLEDM-------LKSCNFSGQ--NCSSEDFSVVYTRYGK-CYTFNGNK 211

  Fly   239 ------QLFSSYLGVSFVLR-SNDEIL-------QSSKSAGFEVLIHESHEIPN------GATP- 282
                  :...:..|:..:|. ..||.|       :::..||..|.||..:|.|.      |.:|
Zfish   212 TSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRETNETTLEAGIRVQIHSQNEPPYIHQLGFGVSPG 276

  Fly   283 -RVFVPGESDAHIML-RPYINRFTKNLKGLSLQKRGCYFSTERRLILSDVYNQINCLAECRTESI 345
             :.||..:......| :|:.|               |..|:|..:...|.|:...|...|.:..:
Zfish   277 FQTFVSCQEQRLTYLPQPWGN---------------CRASSEPVIPGYDTYSVSACRLHCESTQV 326

  Fly   346 LKSCGCIPPKSPIEKSWLICDLKQMQCVIDFDHDEIISGEQK----NCDCLPPCEFNRYEFQSDI 406
            .:.|.|.....|.:..  ||...:::||     |:.::..||    :|.|..||...||  ..::
Zfish   327 QRECNCRMVHMPGDAD--ICAPSKIKCV-----DKALASLQKSTGDSCPCETPCNLTRY--GKEL 382

  Fly   407 RFIKGMINNSIVNTSNQETTNEVRVRVYYDSAIAEELLLDVYENWLTF--------------IGT 457
            ..:|.....|....|.:...:|..:|..:       |:||::...|.:              :|.
Zfish   383 SMVKIPSRGSARYLSRKYQKSEEYIRDNF-------LILDIFFEALNYETIEQKKAYDIAGLLGD 440

  Fly   458 FGGITGLFMGCSFVSVFELI 477
            .||..|||:|.|.:::.|::
Zfish   441 IGGQMGLFIGASILTILEIL 460

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	ASC	96..479	CDD:459966	100/459 (22%)
asic4b	NP_999951.1	ENaC	54..497	CDD:273304	99/452 (22%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:P78348	450..452		1/1 (100%)