Protein Alignment ppk11 and scnn1a

DIOPT Version :10

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_001184124.1
• Gene: scnn1a / 395013
• XenbaseID: XB-GENE-996083
• Length: 633
• Species: Xenopus tropicalis
• Alignment Length: 553
• Identity: 100/553 - (18%)
• Similarity: 181/553 - (32%)
• Gaps: 215/553 - (38%)

  Fly    93 FEIYCEMASIHG-FHIFVGAKTWQRILWWLLICNAVLLSFTL----------------VIMSLSM 140
            ||.:|...:||| ..:........:..:||::   .|.:|.|                |.::|::
 Frog    23 FEFFCSNTTIHGAIRLVCSRSNRMKTAFWLVL---FLATFGLMYWQFGLLFGQYFSYPVSINLNV 84

  Fly   141 SKETPTIRFIDTMMKPTAEVPFPAVTICGFN--------------TKE----------------- 174
            :.:               ::||||||:|..|              .||
 Frog    85 NSD---------------KLPFPAVTVCTLNPYRYKAIQNDLQELDKETQRTLYELYKYNSTGVQ 134

  Fly   175 -WMNSSQIVNQRNASWLELLE---------------------------DLALPICPQI------- 204
             |:.::|.|.:.......|||                           ::...:|.:.
 Frog   135 GWIPTNQRVRRDRPGLPHLLELVPPGSKTHRVSRSVIEEELQVKRREWNIGFKLCNETGGDCFYQ 199

  Fly   205 -------KICQWDN-RMVNCLDQLQPIWTLD-QRL-----------------------------C 231
                   .|.:|.. ..:|.|.::.....:| ::|                             |
 Frog   200 TYTSGVDAIREWYRFHYINILARVPEEAAIDGEQLENFIFACRFNEESCTKANYSHFHHAIYGNC 264

  Fly   232 CSFNYNK----QLFSSYL-----GVSFVLRS--NDEILQSSKSAGFEVLIHESHEIPNGATPRVF 285
            .:||.|:    .|:||.:     |::.:||:  :|.|...|..||..||:| .|:.|.......|
 Frog   265 YTFNQNRSGQSNLWSSSMPGIKNGLTLILRTEQHDYIPLLSSVAGARVLVH-GHKEPAFMDDSGF 328

  Fly   286 --VPGESDAHIMLRPYINRF---------------TKNLKGLSLQKRGCYFSTERRLILSDVYNQ 333
              .||...:..|.:..:||.               .|||           |.:|        |.:
 Frog   329 NIPPGMETSIGMKKETVNRMGGKYSDCSEDGSDVDVKNL-----------FESE--------YTE 374

  Fly   334 INCLAECRTESILKSCGC---IPPKSPIE--------KSWLICDLKQMQCVIDFDHDEIISGEQK 387
            ..|:..|...::::.|||   ..|.||.:        |||..|..|   .:|:|..:::
 Frog   375 QVCVRSCFQAAMVERCGCGYAFYPLSPGDEFCDYNKHKSWGHCYYK---LIIEFTSNKL------ 430

  Fly   388 NC--DCLPPCEFNRYEFQSDI-----RFIKGMINNSIVNTSNQETTNEV-RVRVYYDSAIAEELL 444
            .|  .|..||..:.|:..:..     |..:..:.:::....|....|.: ::.:|::....:.:.
 Frog   431 GCFSKCRKPCLVSEYQLTAGYSKWPNRVSQDWVFHTLSRQYNLTDRNGIAKLNIYFEELNYKTIQ 495

  Fly   445 LDVYENWLTFIGTFGGITGLFMGCSFVSVFELI 477
            .....|.:..:...|....|:.|.|.:||.|::
 Frog   496 ESPTINMVMLLSLLGSQWSLWFGSSVLSVVEML 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	ASC	96..479	CDD:459966	98/550 (18%)
scnn1a	NP_001184124.1	ENaC	18..602	CDD:273304	100/553 (18%)