DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk11 and ppk12

DIOPT Version :9

Sequence 1:	NP_001334672.1	Gene:	ppk11 / 34299	FlyBaseID:	FBgn0065109	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster

Alignment Length:	527	Identity:	124/527 - (23%)
Similarity:	198/527 - (37%)	Gaps:	131/527 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    96 YCEMASIHGFHIFV---GAKTWQRILWWLLICNAVLLSFTLVIMSLSMSKETPTIRFIDTMMKPT 157
            :....|:||.. ||   |..:|:|..:......|::::..|:.........||.|..|.......
  Fly    29 FLNQTSLHGLK-FVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSI 92

  Fly   158 AEVPFPAVTICGFNTKEWMNSSQIVNQRNAS----WLELL------------EDLALP--ICPQI 204
            .:|||||:|||..|.   :..|.:.|.|..|    .|:||            |:.:..  :...:
  Fly    93 LKVPFPAITICNMNQ---VQRSLVANYREGSNESALLKLLCESDSWESSEADEEFSASNFVTNNL 154

  Fly   205 KICQWDN-------RMV----------NCLDQLQPIWTLDQRLCCSFNY-------------NKQ 239
            ||.::.:       ||:          ||....|.|.| |:.|||.||:             |:.
  Fly   155 KISEFVSNHSQSCERMLLFCRFSAVERNCSQLFQQILT-DEGLCCVFNFQPPEYLYKPFANNNRN 218

  Fly   240 LFSS--------------------------------YLGVSFVL--RSNDEILQSSKSAGFEVLI 270
            |.:|                                .||.:.||  ...:....|:...||:|..
  Fly   219 LTNSDGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEYYCSSTNGPGFKVYF 283

  Fly   271 HESHEIPNGATPRVFVPG-------ESDAHI-MLRPYINRFTKNLKGLSLQKRGCYFSTERRLIL 327
            |...|:     |:|...|       |::..| |:|.   .....::.:|...|.|.|..|:.||.
  Fly   284 HNPIEV-----PKVKEAGLISAIGYETNYRIEMVRA---EAVPAIRSISRDGRQCLFKNEKELIF 340

  Fly   328 SDVYNQINCLAECRTESILKSCGCIPPKSP-IEKSWLICDLKQMQCVIDFDHDEIISGEQKNC-- 389
            ..:|.::||..||....:..:|.|||...| |..:..||.:....||..........|..| |
  Fly   341 YRIYTRLNCENECLAAFLYDTCSCIPFDHPLIYSNASICSMGDTSCVRRAQRASNRPGWAK-CRQ 404

  Fly   390 DCLPPCEFNRYEFQSDIRFIKGMIN----NSIVNTSNQE--TTNEVRVRVYYDSAIAEELLLDVY 448
            .|||.| |:.....|...|.....|    |::|.:.|:.  :.|...:.||:..::......:.|
  Fly   405 QCLPSC-FDLNYLASGFSFPLASNNFQLANALVESFNKSYLSKNIAVINVYFRESVYYGNTKNAY 468

  Fly   449 ENWLTFIGTFGGITGLFMGCSFVSVFELIFFSCVRPTCNWLTRQQILWRRR---------RNQRV 504
            .....|:...||:.|||||.|.:|:.|:::|..::|..     :..:|:|.         ::...
  Fly   469 VGLTEFLSNVGGVMGLFMGFSVISLAEILYFLILKPLA-----ELFVWKRSSHVDSEKSLKHNAF 528

  Fly   505 GITESRS 511
            ||.:.:|
  Fly   529 GIEKGQS 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	None
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	117/484 (24%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	117/484 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456736
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm14160
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840