DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk11 and ppk8

DIOPT Version :9

Sequence 1:	NP_001334672.1	Gene:	ppk11 / 34299	FlyBaseID:	FBgn0065109	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_001036260.3	Gene:	ppk8 / 318213	FlyBaseID:	FBgn0052792	Length:	569	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	125/525 - (23%)
Similarity:	205/525 - (39%)	Gaps:	107/525 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    80 ARNDDGLCKRKTGFEIYCEMASIHGFHIFVGAKTWQRILWWLLICNAVLLSFTLVIMSLSMSK-- 142
            :||.|..|:..|          |||......:|.......:..|...|:||..:.::..:..|
  Fly    36 SRNTDEFCRNTT----------IHGLKYINNSKLRSSDRLFFGIALLVVLSLAIYLIQDAFDKWN 90

  Fly   143 ETPTIRFIDTMMKPTAEVPFPAVTICGFN------TKEWMNSS----------------QIVNQR 185
            ..|.|..||..:...|..||||||||..|      .:.:.|.|                ::|...
  Fly    91 TNPVIVGIDPELTSIANEPFPAVTICNLNQALAERVEHFSNDSVEFAMLQLLCRRKVDVELVKTN 155

  Fly   186 NASWLELLEDLALPICPQIKICQWDNRMVNCLDQLQPIWTLDQRLCCSFN-------YNKQLFSS 243
            ::.|.|.:.:::.|....:..|::......|.....||.| |:.|||.||       |.|::..|
  Fly   156 DSRWEEFILNISQPCNSMVIHCRFGADDYECARLFHPIVT-DEGLCCVFNMLHPRFMYRKRVPYS 219

  Fly   244 Y--------------------------------------------LGVSFVL--RSNDEILQSSK 262
            :                                            ||:|..|  :::.....||.
  Fly   220 HRNISLPEGFHAVNWHAELGYRKRGFQPDGDNPLYPRRAQGTGESLGLSLTLDVQADAYYCSSSS 284

  Fly   263 SAGFEVLIHESHEIPNGATPRVFVPGESDAHIMLRPYINRFTKNLKGLSLQKRGCYFSTERRLIL 327
            |.||::.:|..:|.||.....|.:....:..:.:.|......|:|:.:..:.|.|.|..|.:|..
  Fly   285 SIGFKIALHSPNESPNVRETGVLLAPGMETKLRIDPSKILTEKHLRNVDRRSRRCLFHNELKLRW 349

  Fly   328 SDVYNQINCLAECRTESILKSCGCIPPKSP-IEKSWLICDLKQMQCVIDFDHDEIISGEQKNCDC 391
            ...|.|.||:|||.:..:::.|||:....| :..:..||.|.:.:||.......||:.|....:|
  Fly   350 FAHYTQRNCVAECLSGWLIRHCGCVTFYMPRLNANDTICPLHKRECVELIRFRTIIAMESCLDEC 414

  Fly   392 LPPC---EFNRYEFQSDIRF--IKGMINNSIVNTSNQETTNEVR-VRVYYDSAIAEELLLDVYEN 450
            ||.|   .|:...:.:.|..  .:...:|...|.::......|. |.:|:............:..
  Fly   415 LPSCFDLSFSAIAYSTRISLDGFRETPSNGGWNFTDAYVERSVAVVNMYFKDPTFRANKQTEFIG 479

  Fly   451 WLTFIGTFGGITGLFMGCSFVSVFELIFFSCVRP--TCNWLTRQQILWRRRRNQ-RV-GITESRS 511
            :..|:...||:.|||:|.||:|:.|.::|:.:||  ||:.:        |:.|| || .:...||
  Fly   480 FSDFLSGVGGLMGLFLGFSFLSIAECVYFALIRPCRTCSEI--------RQLNQPRVHQMNLKRS 536

  Fly   512 LGPAN 516
            ..|.|
  Fly   537 PTPGN 541

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	None
ppk8	NP_001036260.3	ASC	42..508	CDD:279230	108/476 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456730
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000867
OrthoInspector	1	1.000	-	-		otm14160
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.840