Protein Alignment ppk11 and Scnn1a

DIOPT Version :9

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 613
• Identity: 122/613 - (19%)
• Similarity: 183/613 - (29%)
• Gaps: 247/613 - (40%)

  Fly    93 FEIYCEMASIHGFHIFVGAK--TWQRILW---WLLICNAVLLSFTLVI-------MSLSMSKETP 145
            |:.:|...:|||....|.:|  ..:...|   ||.....:...|.|:.       :||:::..:.
  Rat    85 FQFFCNNTTIHGAIRLVCSKHNRMKTAFWAVLWLCTFGMMYWQFALLFEEYLSYPVSLNINLNSD 149

  Fly   146 TIRFIDTMMKPTAEVPFPAVTICGFN------TKEWMNSSQIVNQR--------NASWLEL---- 192
                         ::.|||||:|..|      .||.:.....:.::        |:|:...
  Rat   150 -------------KLVFPAVTVCTLNPYRYTEIKEELEELDRITEQTLFDLYKYNSSYTRQAGAR 201

  Fly   193 --------------LEDLALP---------------------------------ICPQIK----- 205
                          |:.|..|                                 :|.|.|
  Rat   202 RRSSRDLLGAFPHPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKDWKIGFQLCNQNKSDCFY 266

  Fly   206 ---------ICQWDN-RMVNCLDQLQP-------------IWT--LDQRLCCSFNY--------- 236
                     :.:|.. ..:|.|.:|..             |:|  .:|..|...||
  Rat   267 QTYSSGVDAVREWYRFHYINILSRLSDTSPALEEEALGNFIFTCRFNQAPCNQANYSKFHHPMYG 331

  Fly   237 ---------NKQLFSSYL-----GVSFVLRS--NDEILQSSKSAGFEVLIHESHEIPNGATPRVF 285
                     |..|:.|.:     |:|..||:  ||.|...|...|..|::|       |.....|
  Rat   332 NCYTFNDKNNSNLWMSSMPGVNNGLSLTLRTEQNDFIPLLSTVTGARVMVH-------GQDEPAF 389

  Fly   286 VPGESDAHIMLRPYINRFTKNLKGLSLQKR------GCYFS-TERRLILSDV---------YNQI 334
            :   .|....|||.:.      ..:|::|.      |.|.. ||..   |||         |.|.
  Rat   390 M---DDGGFNLRPGVE------TSISMRKEALDSLGGNYGDCTENG---SDVPVKNLYPSKYTQQ 442

  Fly   335 NCLAECRTESILKSCGC----IPPKSPIE-------KSWLICDLKQMQCVIDFDHDEIISGEQKN 388
            .|:..|..|:::|.|||    .|....:|       .||..|..| :|.....|.....|
  Rat   443 VCIHSCFQENMIKKCGCAYIFYPKPKGVEFCDYRKQSSWGYCYYK-LQGAFSLDSLGCFS----- 501

  Fly   389 CDCLPPCEFNRYEF------------QSDIRFIKGMINNSIVNTS--------------NQETTN 427
             .|..||....|:.            |..|..:..:.||..:|..              |.:|.:
  Rat   502 -KCRKPCSVINYKLSAGYSRWPSVKSQDWIFEMLSLQNNYTINNKRNGVAKLNIFFKELNYKTNS 565

  Fly   428 EVRVRVYYDSAIAEELLLDVYENWLTFIGTFGGITGLFMGCSFVSVFEL--IFFSCVRPTCNWLT 490
            |      ..|.....||.::...|           .|:.|.|.:||.|:  :.|..:..|...|.
  Rat   566 E------SPSVTMVSLLSNLGSQW-----------SLWFGSSVLSVVEMAELIFDLLVITLLMLL 613

  Fly   491 R--QQILWRRRRNQRVGITESRSLGPAN 516
            |  :...|...|..| |..|..|. ||:
  Rat   614 RRFRSRYWSPGRGAR-GAREVAST-PAS 639

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	None
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	122/613 (20%)
		deg-1	88..600	CDD:273309	109/567 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345696
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740