Protein Alignment ppk11 and Scnn1b

DIOPT Version :9

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: NP_036780.1
• Gene: Scnn1b / 24767
• RGDID: 3640
• Length: 638
• Species: Rattus norvegicus
• Alignment Length: 582
• Identity: 105/582 - (18%)
• Similarity: 187/582 - (32%)
• Gaps: 217/582 - (37%)

  Fly    96 YCEMASIHGFHIFVGAKTWQRILWWL-------LIC--NAVLLSFTL---VIMSLSMSKETPTIR 148
            ||...:.||....:.....::.:|:|       |:|  ..|.:...|   |.:||||..:|
  Rat    29 YCNNTNTHGPKRIICEGPKKKAMWFLLTLLFACLVCWQWGVFIQTYLSWEVSVSLSMGFKT---- 89

  Fly   149 FIDTMMKPTAEVPFPAVTICG----------------------------------FNTKEWMNSS 179
                       :.|||||:|.                                  .||...:|.:
  Rat    90 -----------MNFPAVTVCNSSPFQYSKVKHLLKDLYKLMEAVLDKILAPKSSHTNTTSTLNFT 143

  Fly   180 -------QIVNQRNASW---LELLED-------------------LALPIC-PQIKIC------- 207
                   .::::||...   |.|..|                   :|:.:| ....:|
  Rat   144 IWNHTPLVLIDERNPDHPVVLNLFGDSHNSSNPAPGSTCNAQGCKVAMRLCSANGTVCTFRNFTS 208

  Fly   208 ------QW------------------------DNRMVNCL--------DQLQPIWTLDQRLCCSF 234
                  :|                        |..::.||        ....||:..|...|..|
  Rat   209 ATQAVTEWYILQATNIFSQVLPQDLVGMGYAPDRIILACLFGTEPCSHRNFTPIFYPDYGNCYIF 273

  Fly   235 NY---NKQLFSSYLGVSFVLR------SNDEILQSSKSAGFEVLIHESHEIPNGATPRVFVPG-- 288
            |:   .|.|.|:..|..|.|:      ..|.:...:.:||..:::||....|......::...
  Rat   274 NWGMTEKALPSANPGTEFGLKLILDIGQEDYVPFLASTAGARLMLHEQRTYPFIREEGIYAMAGT 338

  Fly   289 ESDAHIML-------RPYINRFTKNLKGLSLQKRGCYFSTERRLILSDVYNQINCLAECRTESIL 346
            |:...::|       .|| :..|.|...:::|.....::|        .|:...||..|..:.::
  Rat   339 ETSIGVLLDKLQGKGEPY-SPCTMNGSDVAIQNLYSDYNT--------TYSIQACLHSCFQDHMI 394

  Fly   347 KSCGC---IPPKSPIEK--------SWLICDLKQMQCVIDFDHDEIISGEQKNC--DCLPPCEFN 398
            .:|.|   :.|....||        .|..|.|.....|:          :::.|  .|...|...
  Rat   395 HNCSCGHYLYPLPAGEKYCNNRDFPDWAYCYLSLQMSVV----------QRETCLSMCKESCNDT 449

  Fly   399 RYEF---------QSDIRFIKGMINNSIVNTSNQETTNE--VRVRVYYDS----AIAEELLLDVY 448
            :|:.         ::...:|..:::.....:||...:.:  |::.:|:..    .|.|....::.
  Rat   450 QYKMTISMADWPSEASEDWILHVLSQERDQSSNITLSRKGIVKLNIYFQEFNYRTIEESPANNIV 514

  Fly   449 ENWLTFIGTFGGITGLFMGCSFVSVFEL--IFFSCVRPTCNWLTRQQIL-----WRRRRNQR 503
              ||  :...||..|.:||.|.:.:.|.  |....:     |:|..:::     .||||.||
  Rat   515 --WL--LSNLGGQFGFWMGGSVLCLIEFGEIIIDFI-----WITVIKLVASCKGLRRRRPQR 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	None
Scnn1b	NP_036780.1	ENaC	21..621	CDD:273304	105/582 (18%)
		deg-1	29..538	CDD:273309	95/546 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	598..620

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345646
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740