DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk11 and del-10

DIOPT Version :9

Sequence 1:	NP_001334672.1	Gene:	ppk11 / 34299	FlyBaseID:	FBgn0065109	Length:	516	Species:	Drosophila melanogaster
Sequence 2:	NP_495302.3	Gene:	del-10 / 174069	WormBaseID:	WBGene00020897	Length:	1069	Species:	Caenorhabditis elegans

Alignment Length:	473	Identity:	95/473 - (20%)
Similarity:	161/473 - (34%)	Gaps:	117/473 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   100 ASIHGFHIFVGAKTWQRILWWLLICNAVLLSFTLVIMSLSMSKETPTIRFIDTMMKPTAEVP--- 161
            |::...|....|....|.||.::|...|:|........:.:....|....|:      ||.|
Worm    78 ANMDAVHHLNAASPVTRGLWCMIIIAFVILVLVQCYSQIKLYISEPVATNIE------AEYPSKI 136

  Fly   162 -FPAVTICGFN--TKEWMNSSQIVNQRN-----------------------ASW----LELLEDL 196
             ||.|.||..|  ...::...:|:|:|:                       .||    ::.|...
Worm   137 SFPTVAICNNNQFRLTYLTGGRIMNRRSKSISGSLLSTGHDVESVFDTVLRKSWDMDAVKFLRSA 201

  Fly   197 ALPICPQIKICQWDNRMVNCLDQLQPIWTLDQRLCCSFNYNK----QLFSSYLGVSFVLRSNDEI 257
            |......|..|.|.|.....|...:.:|| ...||.:.|.:.    ::..|..|....|..|.|.
Worm   202 AHWKSRMILGCTWPNGTSCKLSDFKAVWT-TTGLCWAINTDPHNPYEVTGSGEGHGLRLLLNVES 265

  Fly   258 ----------LQSSKSAGFEVLIHESHEIPNGATPRVFVPGESDAHIMLRPYINRFTKNLKGLSL 312
                      .::....|.::||:...:||:.:...|.||   ..:.|..|:..:....|.|:.
Worm   266 YERVDACTKHFRTKTLPGLKILIYNQTDIPDSSMNGVNVP---SGYSMDIPFKMQHRSKLTGVH- 326

  Fly   313 QKRGCYFSTERRLILSDVYNQINCLAEC-----RTESILKSCGCIPPKSPIEKSWLICDLKQMQC 372
                |....:.::..|..:|....:..|     .|| :..||.|...::....|   .|:|...|
Worm   327 ----CIEENDEQIEASTDFNNPENIRTCTLRRYMTE-VENSCHCTLRRAYTSNS---TDVKMKAC 383

  Fly   373 VIDFDHDEIISGEQKNCD----------CLPPCEFNRYEFQSDIRFIKGMINNSIVNTSNQETTN 427
            .:    |:.....||...          |||||:...|....|:..:...:..:::....::..:
Worm   384 NV----DQYFGCAQKAMQRIREEGTASTCLPPCKSIDYTAWQDMNRLPQNLMPALIEEQEEDDED 444

  Fly   428 EVRVRVYYDSAIAEELLLDVYENWLTFIGTFGGITGLFMGCSFVSVFELIFFSCVRPTCNWLTRQ 492
            :|           |:..||  || ::|....||.|                |||  ....:|..:
Worm   445 DV-----------EQEELD--EN-VSFSTVSGGET----------------FSC--EDSAYLDDK 477

  Fly   493 QILWRRRRNQRVGITESR 510
            |::..:|...|....::|
Worm   478 QVMRIKRDAHRAYEMQAR 495

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	None
del-10	NP_495302.3	ASC	83..>419	CDD:279230	75/358 (21%)
del-10	NP_495302.3	ASC	<789..849	CDD:279230
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810