Protein Alignment ppk11 and Asic2

DIOPT Version :10

• Sequence 1: NP_001334672.1
• Gene: ppk11 / 34299
• FlyBaseID: FBgn0065109
• Length: 516
• Species: Drosophila melanogaster
• Sequence 2: XP_006532059.1
• Gene: Asic2 / 11418
• MGIID: 1100867
• Length: 596
• Species: Mus musculus
• Alignment Length: 524
• Identity: 102/524 - (19%)
• Similarity: 170/524 - (32%)
• Gaps: 204/524 - (38%)

  Fly   102 IHGFHIFVGAKT------WQRILWWLLICNA--VLLSFT--LVIMSLSMSKETPTIRFIDTMMKP 156
            :||.......:|      .:|.||.|..|.:  :|||::  .::..||....|...|      :.
Mouse    66 LHGLRHMCAGRTAAGGSFQRRALWVLAFCTSLGLLLSWSSNRLLYWLSFPSHTRVHR------EW 124

  Fly   157 TAEVPFPAVTICGFNTKEWMNSSQ------------IVNQRNA---------------SWLELLE 194
            :.::||||||:|..|...:...|:            ::..|.|               .|...|.
Mouse   125 SRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLPNRTARPLVSELLRGDEPRRQWFRKLA 189

  Fly   195 DLALPICPQ--------------------IKICQWDNRM--------VNC--------------- 216
            |..|.:.|:                    :..|::...:        |:|
Mouse   190 DFRLFLPPRHFEGISAAFMDRLGHQLEDMLLSCKYRGELCGPHNFSSVSCPPREPALSDPALPRS 254

  Fly   217 ---------LDQLQPIWTLDQRLCCSFNY---NKQLFSSYL-----GVSFVLR-SNDEIL----- 258
                     .....|::|...: |..||.   .|.|.::..     |:..:|. ..||.|
Mouse   255 PEALRWAPGTGHQAPVFTKYGK-CYMFNSGEDGKPLLTTVKGGTGNGLEIMLDIQQDEYLPIWGE 318

  Fly   259 --QSSKSAGFEVLIHESHEIP------NGATP--RVFVPGESDAHIMLRPYINRFTKNLKGLSLQ 313
              :::..||.:|.||...|.|      .|..|  :.||..:......|.|
Mouse   319 TEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQTFVATQEQRLTYLPP--------------- 368

  Fly   314 KRGCYFSTERRLILSDVYNQINCLAECRTESILKSCGC----IPPKSPIEKSWLICDLKQMQCVI 374
            ..|...|:|..|....||:...|..:|.|..|:::|.|    :|..:|      .|..:|
Mouse   369 PWGECRSSEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAP------FCTPEQ----- 422

  Fly   375 DFDHDE-------IISGEQKN-CDCLPPCEFNRYE---------FQSDIRFIKGMINNSIVNTSN 422
               |.|       :::.:..| |.|..||...||.         .::..::::...|.|
Mouse   423 ---HKECAEPALGLLAEKDSNYCLCRTPCNLTRYNKELSMVKIPSKTSAKYLEKKFNKS------ 478

  Fly   423 QETTNEVRVRVYYDSAIAEELL-LDVYENWLTF--------------IGTFGGITGLFMGCSFVS 472
                         :..|:|.:| ||::...|.:              :|..||..|||:|.|.::
Mouse   479 -------------EKYISENILVLDIFFEALNYETIEQKKAYEVAALLGDIGGQMGLFIGASILT 530

  Fly   473 VFEL 476
            :.||
Mouse   531 ILEL 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk11	NP_001334672.1	ASC	96..479	CDD:459966	102/524 (19%)
Asic2	XP_006532059.1	ENaC	64..590	CDD:273304	102/524 (19%)