Protein Alignment CG17633 and CPA6

DIOPT Version :10

• Sequence 1: NP_609310.2
• Gene: CG17633 / 34297
• FlyBaseID: FBgn0032144
• Length: 430
• Species: Drosophila melanogaster
• Sequence 2: NP_065094.3
• Gene: CPA6 / 57094
• HGNCID: 17245
• Length: 437
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 117/349 - (33%)
• Similarity: 188/349 - (53%)
• Gaps: 38/349 - (10%)

  Fly    82 LEILGKSEIKYELQSRDVQKSLDEIDEKVAIKG---------RATTAYNWAQYYELDDTYAWLQS 137
            |..|.::.|:|::...|:||:|:        ||         |:.:.||:..|:.|::...|:..
Human    95 LAFLQEANIQYKVLIEDLQKTLE--------KGSSLHTQRNRRSLSGYNYEVYHSLEEIQNWMHH 151

  Fly   138 LAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWIAPAAATFIIN 202
            |.:|:.|::.:...|::|:|||:..:|:.:     ..:.|..::::.||||||||.||...:.:.
Human   152 LNKTHSGLIHMFSIGRSYEGRSLFILKLGR-----RSRLKRAVWIDCGIHAREWIGPAFCQWFVK 211

  Fly   203 Q-LLTSEVE-NIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRTPYG--SCFGADPNRNWGF 263
            : |||.:.: .::::..:..:|::|..|.|||.::.|.:|.|||||:...  .|.|.|.||||..
Human   212 EALLTYKSDPAMRKMLNHLYFYIMPVFNVDGYHFSWTNDRFWRKTRSRNSRFRCRGVDANRNWKV 276

  Fly   264 HWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHT-SDL 327
            .|.:.|||...|.|||.||...||.|..:::.|:...:..::.|||.|||:|.|||||.:. :.:
Human   277 KWCDEGASMHPCDDTYCGPFPESEPEVKAVANFLRKHRKHIRAYLSFHAYAQMLLYPYSYKYATI 341

  Fly   328 PDNVADFEKVFDASIAAVN---KRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRP 389
            |    :|..|..|:..|||   ..||..|..|.....:|.::|:|:|||| ...:..||.:|||
Human   342 P----NFRCVESAAYKAVNALQSVYGVRYRYGPASTTLYVSSGSSMDWAY-KNGIPYAFAFELR- 400

  Fly   390 SSTSYLTGFKLPAEQIVPASEELL 413
             .|.|. ||.||...|.|...|.:
Human   401 -DTGYF-GFLLPEMLIKPTCTETM 422

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	Propep_M14	33..105	CDD:460505	8/22 (36%)
		Zn_pept	125..407	CDD:214748	102/289 (35%)
CPA6	NP_065094.3	Propep_M14	43..118	CDD:460505	8/30 (27%)
		M14_CPA6	138..436	CDD:349444	104/298 (35%)