DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG17633 and Cpa3

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_062173.1	Gene:	Cpa3 / 54242	RGDID:	2390	Length:	417	Species:	Rattus norvegicus

Alignment Length:	421	Identity:	131/421 - (31%)
Similarity:	226/421 - (53%)	Gaps:	24/421 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 FALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSD-SIMFLDGVH--LVGADIQ 70
            |.|:.::.| :::...|::|..::::|..::.||..:||:|..:.: ...:.|.:|  .|...:.
  Rat     4 FLLMGVIYS-TLAIAPVQFDREKVFRVKLQDEKQASILKNLTQTIELDFWYPDAIHDIAVNMTVD 67

  Fly    71 IIVAPHKVPDFLEILGKSEIKYELQSRDVQKSLD-EIDEKVAIKGRATTAYNWAQYYELDDTYAW 134
            ..|...:.......|.:.::.||:...|:|:.:| :.|.|..|.||    :::|:|.:.:...:|
  Rat    68 FRVTEKESQTIQSTLEQHKMDYEILINDLQEEIDKQFDVKEEIAGR----HSYAKYNDWNKIVSW 128

  Fly   135 LQSLAQTNPGVVTLIEGGKTYQGRSILGVKI-TKGGETINGKAKPGIFLEAGIHAREWIAPAAAT 198
            .:.:.:.:|.:|:.|:.|.|.:...:..:|| .|.||      :..||::.|||||||::||...
  Rat   129 TEKMVEKHPEMVSRIKIGSTVEDNPLYVLKIGRKDGE------RKAIFMDCGIHAREWVSPAFCQ 187

  Fly   199 FIINQLLTSEVEN--IKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRT--PYGSCFGADPNR 259
            :.:.|...|..:|  :.:|.:...:||||..|.|||:::.|.:|:|||.|:  |..:|.|.|.||
  Rat   188 WFVYQAAKSYGKNKIMTKLLDRMNFYVLPVFNVDGYIWSWTKDRMWRKNRSKNPNSTCIGTDLNR 252

  Fly   260 NWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLLYPYGHT 324
            |:...|:....:.:.|...|.||:..||.||.:::.||......::.|::.|:|||.||:|||:|
  Rat   253 NFDVSWDSSPNTDNPCLSVYRGPAPESEKETKAVTNFIRSHLNSIKAYITFHSYSQMLLFPYGYT 317

  Fly   325 SDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMAFCYELRP 389
            ..||.|..|..||...:...::.||.|.|..|.|...||..:|:|:||||.. .::..|.:|||.
  Rat   318 IKLPPNHQDLLKVARIATDVLSSRYETRYIYGPIASTIYKTSGSSLDWAYDL-GIKHTFAFELRD 381

  Fly   390 SSTSYLTGFKLPAEQIVPASEELLDSIVAMA 420
            ...|   ||.||..:|.|..:|.:.|:..:|
  Rat   382 KGKS---GFLLPESRIKPTCKETMLSVKFIA 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	115/373 (31%)
		Propep_M14	34..105	CDD:280416	16/74 (22%)
		M14_CP_A-B_like	125..423	CDD:199844	104/301 (35%)
Cpa3	NP_062173.1	Propep_M14	28..102	CDD:280416	15/73 (21%)
Cpa3	NP_062173.1	Peptidase_M14_like	114..413	CDD:299699	105/306 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351633
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	262	1.000	Inparanoid score	I3014
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm8990
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	10	9.800