DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG17633 and cpa4

DIOPT Version :9

Sequence 1:	NP_609310.2	Gene:	CG17633 / 34297	FlyBaseID:	FBgn0032144	Length:	430	Species:	Drosophila melanogaster
Sequence 2:	NP_001002217.1	Gene:	cpa4 / 431764	ZFINID:	ZDB-GENE-040704-61	Length:	417	Species:	Danio rerio

Alignment Length:	419	Identity:	144/419 - (34%)
Similarity:	239/419 - (57%)	Gaps:	40/419 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 LFALLAIVASASVSAERVRYDNYRMYKVNSENAKQLEVLKDLEGSSDSIMFLDGVHLV-GADIQI 71
            :||||..|....:      ::..::.::::|:...:.:||:|:..|....:..|.... ..|:::
Zfish     7 VFALLVAVHCKEL------FNGDQVLRIHAESEDHIHILKELDEDSGLDFWTHGFSTERPVDVRV 65

  Fly    72 IVAPH----KVPDFLEILGKSEIKYELQSRDVQKSLDEIDEKVAIKGRATT-----AYNWAQYYE 127
               ||    .|.|||:   ::.|.:.:...:||..|||  :|..:...|.|     .:::|.|::
Zfish    66 ---PHASLYAVKDFLK---ENNIPFTVMINNVQDLLDE--QKAEMVSNAETERNAKIFDFAAYHD 122

  Fly   128 LDDTYAWLQSLAQTNPGVVTLIEGGKTYQGRSILGVKITKGGETINGKAKPGIFLEAGIHAREWI 192
            ||..|:::.:|..::|.:::.|..|.:|:.|.:..:|.:.|||.     :|.|:::||||||||:
Zfish   123 LDTIYSFMDTLVASHPNLISKINIGNSYENRPMYALKFSTGGEN-----RPAIWIDAGIHAREWV 182

  Fly   193 APAAATFIINQLLTS-EVE-NIKELAENYTWYVLPHANPDGYVYTHTTNRLWRKTRT--PYGSCF 253
            ..|:|.:|.|::.:. .|: ::..|......|::...|||||.:|||.||:|||||:  |..||.
Zfish   183 TQASAVWIANKMASDYGVDPSVTSLLGQMDVYLMIVTNPDGYSFTHTDNRMWRKTRSVNPGSSCR 247

  Fly   254 GADPNRNWGFHWNEVGASSSACSDTYAGPSAFSEIETLSLSKFIEGLKGKVQLYLSLHAYSQYLL 318
            |.||||||...:...|||.:.|||:|.||.|.||:|..::...|:| .|..:.::|:|:|||.|:
Zfish   248 GTDPNRNWDAGFGGPGASKNPCSDSYHGPYAHSEVEVKNVVDLIKG-HGNFKSFISIHSYSQLLM 311

  Fly   319 YPYGHT-SDLPDNVADFEKVFDASIAAVNKRYGTTYTGGNIYDAIYPAAGASVDWAYGTQDVRMA 382
            ||||:| :::||. ::...|..|:|..:...|.|.|..|:|...||.|:|.|:||.|.. .::.:
Zfish   312 YPYGYTCTNIPDQ-SELHAVGTAAIKELMSLYNTKYQVGSICKIIYQASGGSIDWTYNI-GIKYS 374

  Fly   383 FCYELRPSSTSYLTGFKLPAEQIVPASEE 411
            |.:|||.:.   |.||.|||.||:|.:||
Zfish   375 FAFELRDTG---LYGFLLPANQIIPTAEE 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG17633	NP_609310.2	MpaA	7..374	CDD:225421	128/380 (34%)
		Propep_M14	34..105	CDD:280416	17/75 (23%)
		M14_CP_A-B_like	125..423	CDD:199844	116/292 (40%)
cpa4	NP_001002217.1	Propep_M14	27..97	CDD:280416	17/75 (23%)
cpa4	NP_001002217.1	M14_CPA	115..415	CDD:133081	117/297 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593496
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2866
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D208397at33208
OrthoFinder	1	1.000	-	-		FOG0000056
OrthoInspector	1	1.000	-	-		mtm6559
orthoMCL	1	0.900	-	-		OOG6_100142
Panther	1	1.100	-	-	O	PTHR11705
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1730
SonicParanoid	1	1.000	-	-		X86
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	11	10.780